Lung cancer poses a significant challenge regarding molecular heterogeneity, as it
encompasses a wide range of molecular alterations and cancer-related pathways. Recent …

In the immunological surveillance against cancer, natural killer (NK) cells are essential
effectors that help eradicate altered cells. The complex interactions that occur between NK …

Non-small cell lung cancer (NSCLC) leads as a primary cause of cancer-related premature
mortality in Western populations. This study leverages cutting-edge gene-expression …

Abstract FoxO1 (Forkhead box O1) belongs to the evolutionarily conserved FoxO subfamily
and is involved in diverse physiologic processes, including apoptosis, cell cycle, DNA …

Background Radiomics, an emerging field, presents a promising avenue for the accurate
prediction of biomarkers in different solid cancers. Lung cancer remains a significant global …

Lung cancer remains a formidable global health challenge, necessitating innovative
therapeutic strategies for improved efficacy. This review explores the untapped potential of …

Gastric cancer (GC) is a prevalent malignancy of the digestive system. Distant metastasis
and chemotherapy resistance are the crucial obstacles to prognosis in GC. Recent research …

Low-grade glioma (LGG) is a prevalent and lethal primary brain malignancy, with most
patients succumbing to recurrence and progression. The signal transducer and activator of …

Abstract Phosphoinositide 3-kinases (PI3Ks) are heterodimers consisting of a p110 catalytic
subunit and a p85 regulatory subunit. The PIK3CA gene, which encodes the p110α, is the …

Endothelial cell (EC) health can be disturbed in various diseases like aging, obesity,
atherosclerosis and type 2 diabetes. Previously, our lab showed that female ECs retain a …