Turning the spotlight to cholinergic pharmacotherapy of the human language system

G Dávila, MJ Torres-Prioris, D López-Barroso… - CNS drugs, 2023 - Springer
Even though language is essential in human communication, research on pharmacological
therapies for language deficits in highly prevalent neurodegenerative and vascular brain …

Language differences among individuals with normal cognition, amnestic and non-amnestic MCI, and Alzheimer's disease

I Liampas, V Folia, R Morfakidou… - Archives of Clinical …, 2023 - academic.oup.com
Objective To investigate differences in language performance among older adults with
normal cognition (CN), mild cognitive impairment (MCI), and Alzheimer's disease (ad) …

Higher total cholesterol concentration may be associated with better cognitive performance among elderly females

K Pang, C Liu, J Tong, W Ouyang, S Hu, Y Tang - Nutrients, 2022 - mdpi.com
Background: The brain contains the highest level of cholesterol in the body, and the total
amount of serum cholesterol in the blood has a huge impact on brain aging and cognitive …

[HTML][HTML] Perfiles Cognitivos-Lingüísticos En Personas Mayores Con Deterioro Cognitivo Leve, Demencia Vascular, Demencia Con Cuerpos De Lewy Y Enfermedad …

C Malpu-Wiederhold, C Farías-Ulloa… - Revista Ecuatoriana …, 2022 - scielo.senescyt.gob.ec
Introducción: Existe una amplia heterogeneidad de síntomas neuropsicológicos reportados
en el envejecimiento patológico. La investigación actual se ha enfocado en la enfermedad …

[HTML][HTML] Atypical cortical hierarchy in Aβ-positive older adults and its reflection in spontaneous speech

R He, J Al-Tamimi, G Sánchez-Benavides… - Brain Research, 2024 - Elsevier
Abnormal deposition of Aβ amyloid is an early neuropathological marker of Alzheimer's
disease (AD), arising long ahead of clinical symptoms. Non-invasive measures of …

Reading and lexical–semantic retrieval tasks outperforms single task speech analysis in the screening of mild cognitive impairment and Alzheimer's disease

I Martínez-Nicolás, F Martínez-Sánchez, O Ivanova… - Scientific Reports, 2023 - nature.com
Age-related cognitive impairment have increased dramatically in recent years, which has
risen the interes in developing screening tools for mild cognitive impairment and Alzheimer's …

Assessment of Language Function in Older Mandarin-Speaking Adults with Mild Cognitive Impairment using Multifaceted Language Tests

YT Tseng, YL Chang, YS Chiu - Journal of Alzheimer's …, 2024 - content.iospress.com
Background: Individuals with amnestic mild cognitive impairment (aMCI), especially for
those with multidomain cognitive deficits, should be clinically examined for determining risk …

Episodic Thinking in Alzheimer's Disease Through the Lens of Language: Linguistic Analysis and Transformer-Based Classification

R He, X Yuan, W Hinzen - American Journal of Speech-Language Pathology, 2024 - ASHA
Purpose: Episodic memory decline is a hallmark of Alzheimer's disease (AD) and linked to
deficits in episodic thinking directed to the future. We addressed the question whether a …

Diagnostic accuracy of multi-component spatial-temporal gait parameters in older adults with amnestic mild cognitive impairment

S Huang, X Hou, Y Liu, P Shang, J Luo, Z Lv… - Frontiers in Human …, 2022 - frontiersin.org
Objective This study aimed to develop a diagnostic model of multi-kinematic parameters for
patients with amnestic mild cognitive impairment (aMCI). Method In this cross-sectional …

Disintegration at the syntax-semantics interface in prodromal Alzheimer's disease: New evidence from complex sentence anaphora in amnestic Mild Cognitive …

B Lust, S Flynn, C Henderson, J Gair… - Journal of …, 2024 - Elsevier
Although diverse language deficits have been widely observed in prodromal Alzheimer's
disease (AD), the underlying nature of such deficits and their explanation remains opaque …