Hydrolyzed low-molecular-weight polysaccharide from Enteromorpha prolifera exhibits high anti-inflammatory activity and promotes wound healing

F Jiang, Y Ding, Y Tian, R Yang, M Quan, Z Tong… - Biomaterials …, 2022 - Elsevier
Increased anti-inflammatory activity is key to accelerating wound healing. In this study, we
prepared three types of water-soluble polysaccharides from Enteromorpha prolifera (PEPs) …

Proteomics-Guided Mining and Characterization of Epoxidase Involved in Camptothecin Biosynthesis from Camptotheca acuminata

X Pu, M Wang, M Chen, X Lin, M Lei… - ACS Chemical …, 2023 - ACS Publications
The detailed metabolic map for camptothecin (CPT) biosynthesis in Camptotheca acuminata
has been proposed according to our combined omics results. However, the CYP450 …

[HTML][HTML] Proteomics-driven noninvasive screening of circulating serum protein panels for the early diagnosis of hepatocellular carcinoma

X Xing, L Cai, J Ouyang, F Wang, Z Li, M Liu… - Nature …, 2023 - nature.com
Early diagnosis of hepatocellular carcinoma (HCC) lacks highly sensitive and specific
protein biomarkers. Here, we describe a staged mass spectrometry (MS)-based discovery …

Proteomic and lipidomic analyses reveal saturated fatty acids, phosphatidylinositol, phosphatidylserine, and associated proteins contributing to intramuscular fat …

J Zhou, Y Zhang, J Wu, M Qiao, Z Xu, X Peng… - Journal of Proteomics, 2021 - Elsevier
Intramuscular fat (IMF) content is an important factor in porcine meat quality. Previous
studies have screened multiple candidate genes related to IMF deposition, but the lipids that …

[HTML][HTML] Time-resolved multiomics analysis of the genetic regulation of maize kernel moisture

J Qu, S Xu, X Gou, H Zhang, Q Cheng, X Wang, C Ma… - The Crop Journal, 2023 - Elsevier
Maize kernel moisture content (KMC) at harvest greatly affects mechanical harvesting,
transport and storage. KMC is correlated with kernel dehydration rate (KDR) before and after …

[HTML][HTML] Serum proteomic analysis identifies SAA1, FGA, SAP, and CETP as new biomarkers for eosinophilic granulomatosis with polyangiitis

J Xiao, S Lu, X Wang, M Liang, C Dong… - Frontiers in …, 2022 - frontiersin.org
Background Eosinophilic granulomatosis with polyangiitis (EGPA) is characterized by
asthma-like attacks in its early stage, which is easily misdiagnosed as severe asthma …

[HTML][HTML] Integrative proteomic profiling of lung tissues and blood in acute respiratory distress syndrome

R Gong, H Luo, G Long, J Xu, C Huang… - Frontiers in …, 2023 - frontiersin.org
Introduction Acute respiratory distress syndrome and acute lung injury (ARDS/ALI) still lack a
recognized diagnostic test and pharmacologic treatments that target the underlying …

[HTML][HTML] Liver transcriptomic and proteomic analyses provide new insight into the pathogenesis of liver fibrosis in mice

L Zhang, Q Zhou, J Zhang, K Cao, C Fan, S Chen… - Genomics, 2023 - Elsevier
Background Liver fibrosis (LF) is a kind of progressive liver injury reaction. The goal of this
study was to achieve a more detailed understanding of the molecular changes in response …

Quantitative phosphoproteomic analysis of mice with liver fibrosis by dia mass spectrometry analysis with prm verification

L Zhang, F Wu, C Fan, S Huang, Y Ma, S Chen… - Journal of …, 2023 - Elsevier
Liver fibrosis (LF), commonly associated with chronic liver diseases, is a major public health
problem worldwide. Protein phosphorylation is not only an important form of protein …

[HTML][HTML] The plasma DIA-based quantitative proteomics reveals the pathogenic pathways and new biomarkers in cervical cancer and high grade squamous …

S Han, J Zhang, Y Sun, L Liu, L Guo, C Zhao… - Journal of clinical …, 2022 - mdpi.com
Objective: The process of normal cervix changing into high grade squamous intraepithelial
lesion (HSIL) and invasive cervical cancer is long and the mechanisms are still not …