Tumors can be divided into 'hot'(T cell inflamed) or 'cold'(T cell noninflamed) according to the
presence of immune cells. In this review, we discuss variables that influence T cell migration …

Context Laboratories must validate all assays before they can be used to test patient
specimens, but currently there are no evidence-based guidelines regarding validation of …

Background Cancer Care Ontario's Program in Evidence-Based Care (pebc) recently
created an evidence-based consensus guideline on the systemic treatment of early breast …

Purpose To calculate the prevalence, localization, and growth of sporadic angiomyolipomas
and to identify the predominant sex in the largest patient population reviewed to date …

Objective Contrast-enhanced spectral mammography (CESM) is a reliable problem solving
tool in the work-up of women recalled from breast cancer screening. We evaluated …

Quantitative biomarkers are key prognostic and predictive factors in the diagnosis and
treatment of cancer. In the clinical laboratory, the majority of biomarker quantitation is still …

Purpose Extension of adjuvant endocrine therapy beyond five years confers only modest
survival benefit in breast cancer patients and carries risk of toxicities. This systematic review …

Materials and Methods: ER, PR, and HER2 by IHC and HER2 oncogene by fluorescent in-
situ hybridization (FISH) were studied on cell blocks of FNA of axillary lymphnodes in 53 of …

Purpose: The impact of neoadjuvant chemotherapy (NACT) on immunohistochemical
markers in breast cancer specimens remains controversial. We designed the current study to …

Progression in digital pathology has yielded new opportunities for a remote work
environment. We evaluated the utility of digital review of breast cancer immunohistochemical …