[HTML][HTML] Idiopathic restless legs syndrome: abnormalities in central somatosensory processing
J Schattschneider, A Bode, G Wasner, A Binder… - Journal of …, 2004 - Springer
Objectives Neurophysiological studies have shown an impairment of temperature
perception in secondary and idiopathic restless legs syndrome (RLS). It is unclear whether …
perception in secondary and idiopathic restless legs syndrome (RLS). It is unclear whether …
Mapping intrinsic functional brain changes and repetitive transcranial magnetic stimulation neuromodulation in idiopathic restless legs syndrome: a resting-state …
C Liu, Z Dai, R Zhang, M Zhang, Y Hou, Z Qi, Z Huang… - Sleep medicine, 2015 - Elsevier
Objective The objectives of this study were, first, to explore differences in brain activity
between normal people and idiopathic restless legs syndrome (RLS) patients during …
between normal people and idiopathic restless legs syndrome (RLS) patients during …
[HTML][HTML] Treatment of restless legs syndrome
CL Comella - Neurotherapeutics, 2014 - Elsevier
Restless legs syndrome (RLS) is a common disorder diagnosed by the clinical
characteristics of restlessness in the legs associated often with abnormal sensations that …
characteristics of restlessness in the legs associated often with abnormal sensations that …
Efficacy of rotigotine transdermal system in severe restless legs syndrome: a randomized, double-blind, placebo-controlled, six-week dose-finding trial in Europe
WH Oertel, H Benes, D Garcia-Borreguero, P Geisler… - Sleep Medicine, 2008 - Elsevier
BACKGROUND: In a pilot placebo-controlled study, low dosages of 0.5–2mg/24h rotigotine
showed a dose-dependent beneficial effect in restless legs syndrome (RLS) patients …
showed a dose-dependent beneficial effect in restless legs syndrome (RLS) patients …
[HTML][HTML] Linkage analysis identifies a novel locus for restless legs syndrome on chromosome 2q in a South Tyrolean population isolate
Restless legs syndrome (RLS) is a common neurological condition with three loci (12q, 14q,
and 9p) described so far, although none of these genes has yet been identified. We report a …
and 9p) described so far, although none of these genes has yet been identified. We report a …
Effectiveness of exercise and pramipexole in the treatment of restless leg syndrome: implications on the dopaminergic system and PTPRD
MA Morais, B Franco, ASS Holanda… - Sleep Medicine, 2023 - Elsevier
Objective Dopaminergic dysfunction, iron reduction and variations in the PTPRD gene
(protein tyrosine phosphatase receptor type delta) may be associated with restless leg …
(protein tyrosine phosphatase receptor type delta) may be associated with restless leg …
Drugs for sleep disorders: mechanisms and therapeutic prospects
E Szabadi - British journal of clinical pharmacology, 2006 - Wiley Online Library
The past decade has witnessed an explosion of knowledge about the neural mechanisms
that control sleep and arousal, triggered by two discoveries relating to the sleep disorder …
that control sleep and arousal, triggered by two discoveries relating to the sleep disorder …
Sleep laboratory studies in restless legs syndrome patients as compared with normals and acute effects of ropinirole: 1. Findings on objective and subjective sleep …
B Saletu, G Gruber, M Saletu, N Brandstätter… - …, 2000 - karger.com
Although the restless legs syndrome (RLS) is a disorder with a relatively high prevalence
rate (8% in Austria) and leads to insomnia and excessive daytime tiredness, there is a …
rate (8% in Austria) and leads to insomnia and excessive daytime tiredness, there is a …
Genetics of restless legs syndrome (RLS): State‐of‐the‐art and future directions
J Winkelmann, O Polo, F Provini… - … : Official Journal of …, 2007 - Wiley Online Library
Several studies demonstrated that 60% of restless legs syndrome (RLS) patients have a
positive family history and it has been suggested that RLS is a highly hereditary trait. To …
positive family history and it has been suggested that RLS is a highly hereditary trait. To …
Restless legs syndrome during and after pregnancy and its relation to snoring
M Sarberg, A Josefsson… - Acta obstetricia et …, 2012 - Wiley Online Library
Objective. To study development of restless legs syndrome (RLS) during and after
pregnancy, and whether RLS is related to snoring or other pregnancy‐related symptoms …
pregnancy, and whether RLS is related to snoring or other pregnancy‐related symptoms …