Genetic variability and haplotype profile of MDR1 (ABCB1) in Roma and Hungarian population samples with a review of the literature
The genetic variability, haplotype profile and ethnic differences of MDR1 polymorphisms in
healthy Roma and Hungarian populations were analyzed and the results were compared …
healthy Roma and Hungarian populations were analyzed and the results were compared …
MDR1 C3435T polymorphism in patients with breast cancer
BACKGROUND: The human multidrug-resistant gene (MDR1) encodes P-glycoprotein
(Pgp), a membrane-bound efflux transporter conferring resistance to a number of natural …
(Pgp), a membrane-bound efflux transporter conferring resistance to a number of natural …
Frequency of the C1236T, G2677T/A and C3435T MDR1 gene polymorphisms in the Serbian population
M Milojkovic, S Stojnev, I Jovanovic… - Pharmacological …, 2011 - Springer
The multi-drug resistance 1 (MDR1) gene encodes for a P-glycoprotein (PGP), which acts as
a gate-keeper against various kinds of xenobiotics. Several single nucleotide …
a gate-keeper against various kinds of xenobiotics. Several single nucleotide …
Theoretical formulation strategies towards neutralizing inter-individual variability associated with tacrolimus immunosuppressant therapy: a case study on …
A Radhakrishnan, G Kuppusamy - Current Drug Metabolism, 2021 - ingentaconnect.com
Individualizing drug therapy and attaining maximum benefits of a drug devoid of adverse
reactions is the benefit of personalized medicine. One of the important factors contributing to …
reactions is the benefit of personalized medicine. One of the important factors contributing to …
ABCB1 C3435T polymorphism is associated with susceptibility to major depression, but not with a clinical response to citalopram in a Turkish population
G Ozbey, B Yucel, SE Taycan, D Kan, NE Bodur… - Pharmacological …, 2014 - Elsevier
Background The ATP-binding cassette sub-family B member 1 (ABCB1) gene, which
encodes the p-glycoprotein at the blood–brain barrier, is investigated for patients' …
encodes the p-glycoprotein at the blood–brain barrier, is investigated for patients' …
[HTML][HTML] Multidrug resistant 1 (MDR1) C3435T and G2677T gene polymorphism: impact on the risk of acute rejection in pediatric kidney transplant recipients
Background Tacrolimus is the backbone drug in kidney transplantation. Single nucleotide
polymorphism of Multidrug resistant 1 gene can affect tacrolimus metabolism consequently it …
polymorphism of Multidrug resistant 1 gene can affect tacrolimus metabolism consequently it …
ABCB1 single nucleotide polymorphisms in the Brazilian population
MAM Scheiner, AM Damasceno, RC Maia - Molecular biology reports, 2010 - Springer
Abstract The ABCB1/MDR-1 gene, which encodes P-glycoprotein, is highly polymorphic. We
analyzed 278 healthy Brazilian individuals through PCR–RFLP to identify ABCB1 variants …
analyzed 278 healthy Brazilian individuals through PCR–RFLP to identify ABCB1 variants …
Association between the MDR1 rs1045642 polymorphism and breast cancer risk: An updated meta‑analysis
L Gong, G Hu, L Xu, Y Chen… - Oncology …, 2024 - spandidos-publications.com
Abstract Multidrug resistance 1 (MDR1) is a transmembrane transporter on the cell
membrane. As an ATP‑dependent efflux pump, MDR1 is mainly responsible for the …
membrane. As an ATP‑dependent efflux pump, MDR1 is mainly responsible for the …
Haplotype-Based Analysis of MDR1/ABCB1 Gene Polymorphisms in a Turkish Population
G Gümüş-Akay, A Rüstemoğlu, A Karadağ… - DNA and Cell …, 2010 - liebertpub.com
The three functional single-nucleotide polymorphisms (SNPs) of the MDR1 gene, C1236T,
G2677T/A, and C3435T, exhibit an interpopulation difference. In this study, we analyzed the …
G2677T/A, and C3435T, exhibit an interpopulation difference. In this study, we analyzed the …
Association of MDR1 C3435T polymorphism with bipolar disorder in patients treated with valproic acid
Abstract P-glycoprotein (P-gp), an efflux transporter protein, is an ABC transporter encoded
by the multidrug resistance 1 gene (MDR1, ABCB1). The common synonymous C3435T …
by the multidrug resistance 1 gene (MDR1, ABCB1). The common synonymous C3435T …