In end-stage lung diseases, the shortage of donor lungs for transplantation and long waiting
lists are the main culprits in the significantly increasing number of patient deaths. New …

Mechanical forces affect the alveolar shape, depending on location and tissue composition,
and vary during the respiratory cycle. This study performs alveolar morphomics in different …

Abstract Background Early diagnosing Chronic Obstructive Pulmonary Disease (COPD) is
relatively difficult. Therefore, the concepts of preserved ratio impaired spirometry (PRISm) …

Objective. To develop a robust technique for calculating regional volume changes within the
lung from x-ray radiograph sequences captured during ventilation, without the use of …

Alterations of the pulmonary vasculature are an important feature of human lung diseases
such as chronic obstructive pulmonary disease, pulmonary hypertension, and …

Significance: Streptococcus pneumoniae (Spn), a facultative anaerobic Gram-positive
human pathogen with increasing rates of penicillin and macrolide resistance, is a major …

The lung promptly responds to edemagenic conditions through functional adaptations that
contrast the increase in microvascular filtration. This review presents evidence for early …

The pulmonary vasculature consists of a large arterial and venous tree with a vast alveolar
capillary network (ACN) in between. Both conducting blood vessels and the gas-exchanging …

Knowledge of the lung vessel morphology in healthy subjects is necessary to improve our
understanding about the functional network of the lung and to recognize pathologic …

Accurate estimation of the absolute number of a particular cell‐type in whole organs is
increasingly important in studies on organogenesis, and the remodelling and repair of …