Sex differences in immunity

NM Wilkinson, HC Chen, MG Lechner… - Annual review of …, 2022 - annualreviews.org
Strong epidemiological evidence now exists that sex is an important biologic variable in
immunity. Recent studies, for example, have revealed that sex differences are associated …

[HTML][HTML] Sex differences in markers of oxidation and inflammation. Implications for ageing

IM de Toda, M González-Sánchez… - Mechanisms of ageing …, 2023 - Elsevier
Sexual dimorphism is a key factor to consider in the ageing process given the impact that it
has on life expectancy. The oxidative-inflammatory theory of ageing states that the ageing …

Sex-related differences in long-COVID-19 syndrome

G Pelà, M Goldoni, E Solinas, C Cavalli… - Journal of Women's …, 2022 - liebertpub.com
Background: Sex differences have been demonstrated in the acute phase of coronavirus
disease 2019 (COVID-19). Women (F) were found to be less prone to develop a severe …

[HTML][HTML] Gender differences in adverse events following the Pfizer-BioNTech COVID-19 vaccine

MS Green, V Peer, A Magid, N Hagani, E Anis… - Vaccines, 2022 - mdpi.com
Background: The adverse events reported from the COVID-19 mRNA vaccines have varied
from very mild, such as pain near the vaccination site, to more severe, with occasional …

[HTML][HTML] Single-cell RNA sequencing reveals the heterogeneity of tumor-associated macrophage in non-small cell lung cancer and differences between sexes

Q Yang, H Zhang, T Wei, A Lin, Y Sun, P Luo… - Frontiers in …, 2021 - frontiersin.org
Non-Small Cell Lung Cancer (NSCLC) is a disease with high morbidity and mortality, which
has sex-related differences in prognosis and immunotherapy efficacy. However, the …

[HTML][HTML] The impact of biological sex on diseases of the urinary tract

L Deltourbe, LL Mariano, TN Hreha, DA Hunstad… - Mucosal …, 2022 - Elsevier
Biological sex, being female or male, broadly influences diverse immune phenotypes,
including immune responses to diseases at mucosal surfaces. Sex hormones, sex …

[HTML][HTML] Why females do better: the X chromosomal TLR7 gene-dose effect in COVID-19

AE Spiering, TJ de Vries - Frontiers in Immunology, 2021 - frontiersin.org
A male sex bias has emerged in the COVID-19 pandemic, fitting to the sex-biased pattern in
other viral infections. Males are 2.84 times more often admitted to the ICU and mortality is …

[HTML][HTML] Role of the humoral immune response during COVID-19: guilty or not guilty?

M Yaugel-Novoa, T Bourlet, S Paul - Mucosal Immunology, 2022 - Elsevier
Systemic and mucosal humoral immune responses are crucial to fight respiratory viral
infections in the current pandemic of COVID-19 caused by the SARS-CoV-2 virus. During …

[HTML][HTML] Consequences of sex differences in Type I IFN responses for the regulation of antiviral immunity

M Pujantell, M Altfeld - Frontiers in immunology, 2022 - frontiersin.org
The immune system protects us from pathogens, such as viruses. Antiviral immune
mechanisms aim to limit viral replication, and must maintain immunological homeostasis to …

[HTML][HTML] Extension and severity of self-reported side effects of seven COVID-19 vaccines in Mexican population

ME Camacho Moll, AM Salinas Martínez… - Frontiers in public …, 2022 - frontiersin.org
A few studies examined the comparative side effects of Coronavirus Disease-19 (COVID-19)
vaccines. We compared the extension and severity of self-reported side effects of seven …