Pharmacological principles guiding prolonged glucocorticoid treatment in ARDS
Current literature addressing the pharmacological principles guiding glucocorticoid (GC)
administration in ARDS is scant. This paucity of information may have led to the …
administration in ARDS is scant. This paucity of information may have led to the …
Prolonged glucocorticoid treatment is associated with improved ARDS outcomes: analysis of individual patients' data from four randomized trials and trial-level meta …
Purpose To investigate the effect of prolonged glucocorticoid treatment for patients with
acute respiratory distress syndrome (ARDS). Methods We conducted two sets of intention-to …
acute respiratory distress syndrome (ARDS). Methods We conducted two sets of intention-to …
The REMAP-CAP (randomized embedded multifactorial adaptive platform for community-acquired pneumonia) study. Rationale and design
There is broad interest in improved methods to generate robust evidence regarding best
practice, especially in settings where patient conditions are heterogenous and require …
practice, especially in settings where patient conditions are heterogenous and require …
Corticosteroids in acute lung injury: the dilemma continues
Acute lung injury (ALI) represents a serious heterogenous pulmonary disorder with high
mortality. Despite improved understanding of the pathophysiology, the efficacy of standard …
mortality. Despite improved understanding of the pathophysiology, the efficacy of standard …
Hydrocortisone infusion for severe community-acquired pneumonia: a preliminary randomized study
M Confalonieri, R Urbino, A Potena… - American journal of …, 2005 - atsjournals.org
We hypothesize that hydrocortisone infusion in severe community-acquired pneumonia
attenuates systemic inflammation and leads to earlier resolution of pneumonia and a …
attenuates systemic inflammation and leads to earlier resolution of pneumonia and a …
Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome: results of a randomized controlled trial
S Tongyoo, C Permpikul, W Mongkolpun… - Critical Care, 2016 - Springer
Background Authors of recent meta-analyses have reported that prolonged glucocorticoid
treatment is associated with significant improvements in patients with severe pneumonia or …
treatment is associated with significant improvements in patients with severe pneumonia or …
Acute eosinophilic pneumonia. Causes, diagnosis, and management
F De Giacomi, R Vassallo, ES Yi… - American journal of …, 2018 - atsjournals.org
Acute eosinophilic pneumonia (AEP) is an uncommon acute respiratory illness of varying
severity that includes presentation as acute respiratory distress syndrome with fatal …
severity that includes presentation as acute respiratory distress syndrome with fatal …
Peripheral muscle strength training in bed-bound patients with COPD receiving mechanical ventilation: effect of electrical stimulation
E Zanotti, G Felicetti, M Maini, C Fracchia - Chest, 2003 - Elsevier
Study objective To compare the effects of active limb mobilization (ALM) with or without
electrical stimulation (ES) on muscle strength, respiratory rate (RR), heart rate, oxygen …
electrical stimulation (ES) on muscle strength, respiratory rate (RR), heart rate, oxygen …
Prolonged low-dose methylprednisolone treatment is highly effective in reducing duration of mechanical ventilation and mortality in patients with ARDS
GU Meduri, RAC Siemieniuk, RA Ness… - Journal of Intensive …, 2018 - Springer
An updated meta-analysis incorporating nine randomized trials (n= 816) investigating low-to-
moderate dose prolonged glucocorticoid treatment in acute respiratory distress syndrome …
moderate dose prolonged glucocorticoid treatment in acute respiratory distress syndrome …
Ventilation-induced chemokine and cytokine release is associated with activation of nuclear factor-κ B and is blocked by steroids
HD HELD, S BOETTCHER, L HAMANN… - American journal of …, 2001 - atsjournals.org
Recent clinical trials have shown that the survival of patients with acute respiratory distress
syndrome (ARDS) is improved by ventilation with reduced volumes. These studies …
syndrome (ARDS) is improved by ventilation with reduced volumes. These studies …