[HTML][HTML] Cracking brain diseases from gut microbes-mediated metabolites for precise treatment

Y Gong, A Chen, G Zhang, Q Shen, L Zou… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
The gut-brain axis has been a subject of significant interest in recent years. Understanding
the link between the gut and brain axis is crucial for the treatment of disorders. Here, the …

Anti-tumor immune potentiation targets-engineered nanobiotechnologies: Design principles and applications

R Jiao, X Lin, Q Zhang, Y Zhang, W Qin, Q Yang… - Progress in Materials …, 2023 - Elsevier
Combined therapeutic strategies hold promises in augmenting antigen release to enhance
anti-tumor immunity, which have garnered attention in numerous scholarly reviews. Beyond …

Multichannel Sonocatalysis Amplifiers Target IDH1‐Mutated Tumor Plasticity and Attenuate Ros Tolerance to Repress Malignant Cholangiocarcinoma

D Wang, X Zhu, X Wang, Q Wang, K Yan… - Advanced Functional …, 2023 - Wiley Online Library
Tumor adaptation‐originated tumor tolerance that compensatory mechanisms (eg, isocitrate
dehydrogenase (IDH) mutation) jointly shape is the dominant obstacle of ROS therapy …

Targeting Vascular Destruction by Sonosensitizer‐Free Sonocatalytic Nanomissiles Instigates Thrombus Aggregation and Nutrition Deprivation to Starve Pancreatic …

Y He, T Wang, Y Song, C Fang, Y Wang… - Advanced Functional …, 2024 - Wiley Online Library
Sonosensitizers in current sonodynamic therapy (SDT) often suffer from poor delivery
efficiency, phototoxicity, and disputed safety. To overcome these issues, a sonosensitizers …

Light-Triggered Nanozymes Remodel the Tumor Hypoxic and Immunosuppressive Microenvironment for Ferroptosis-Enhanced Antitumor Immunity

Z Fan, S Wu, H Deng, G Li, L Huang, H Liu - ACS nano, 2024 - ACS Publications
Cancer immunotherapy holds significant promise for addressing diverse malignancies.
Nevertheless, its efficacy remains constrained by the intricate tumor immunosuppressive …

Calcium peroxide nanoparticles induce endoplasmic reticulum stress for enhanced radiation therapy of osteosarcoma

Z Liu, Z Fu, M Zhao, H Wang, X Ji, J Zhou, W Gu, Y Gu… - Nano Today, 2024 - Elsevier
Radiation therapy (RT) has been widely used in clinics. The expression of various radiation-
resistant proteins limits the curative effect of RT. Endoplasmic reticulum (ER) plays a critical …

[HTML][HTML] Biosynthesis of fungus-based oral selenium microcarriers for radioprotection and immuno-homeostasis shaping against radiation-induced heart disease

C Liu, W Wang, H Lai, Y Chen, L Li, H Li, M Zhan… - Bioactive Materials, 2024 - Elsevier
Radiation-induced heart disease (RIHD), characterized by severe oxidative stress and
immune dysregulation, is a serious condition affecting cancer patients undergoing thoracic …

The Antioxidant Dendrobium officinale Polysaccharide Modulates Host Metabolism and Gut Microbiota to Alleviate High-Fat Diet-Induced Atherosclerosis in ApoE−/− …

J Qi, S Zhou, G Wang, R Hua, X Wang, J He, Z Wang… - Antioxidants, 2024 - mdpi.com
Background: The discovery of traditional plants' medicinal and nutritional properties has
opened up new avenues for developing pharmaceutical and dietary strategies to prevent …

Nanomedicine‐encouraged cellular autophagy promoters favor liver fibrosis progression reversal

C Qian, Y Zhang, X Chen, C Zhu, X Dong, W Chen… - View, 2024 - Wiley Online Library
Liver fibrosis is a major risk factor for hepatocellular carcinoma origin, and its progression
not only correlates with oxidative stress and inflammation, but also is encouraged by …

Baicalin-loaded Polydopamine modified ZIF-8 NPs inhibits myocardial ischemia/reperfusion injury in rats

C Chen, W Liu, X Gu, L Zhang, X Mao… - Journal of Biomaterials …, 2024 - Taylor & Francis
Baicalin (BAN) has shown promise in alleviating myocardial ischemia/reperfusion (I/R)
injury, yet its limited solubility and biocompatibility have hindered its application. Developing …