Intracranial atherosclerotic stenosis: risk factors, diagnosis, and treatment

J Gutierrez, TN Turan, BL Hoh… - The Lancet Neurology, 2022 - thelancet.com
Intracranial atherosclerotic stenosis (ICAS) is one of the most frequent causes of stroke
worldwide and confers one of the greatest risks of recurrent stroke compared with other …

Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 guidelines for the early management of acute ischemic stroke: a …

WJ Powers, AA Rabinstein, T Ackerson, OM Adeoye… - Stroke, 2019 - Am Heart Assoc
Background and Purpose—The purpose of these guidelines is to provide an up-to-date
comprehensive set of recommendations in a single document for clinicians caring for adult …

[HTML][HTML] Ticagrelor versus Clopidogrel in CYP2C19 Loss-of-Function Carriers with Stroke or TIA

Y Wang, X Meng, A Wang, X Xie, Y Pan… - … England Journal of …, 2021 - Mass Medical Soc
Background Comparisons between ticagrelor and clopidogrel for the secondary prevention
of stroke in CYP2C19 loss-of-function carriers have not been extensively performed …

Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4· 5 H of stroke onset: an open-label, blinded-endpoint …

PJ Mitchell, B Yan, L Churilov, RJ Dowling, SJ Bush… - The Lancet, 2022 - thelancet.com
Background The benefit of combined treatment with intravenous thrombolysis before
endovascular thrombectomy in patients with acute ischaemic stroke caused by large vessel …

Clopidogrel and aspirin in acute ischemic stroke and high-risk TIA

SC Johnston, JD Easton, M Farrant… - … England Journal of …, 2018 - Mass Medical Soc
Background Combination antiplatelet therapy with clopidogrel and aspirin may reduce the
rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient …

Canadian stroke best practice recommendations: secondary prevention of stroke update 2020

DJ Gladstone, MP Lindsay, J Douketis… - Canadian Journal of …, 2022 - cambridge.org
The 2020 update of the Canadian Stroke Best Practice Recommendations (CSBPR) for the
Secondary Prevention of Stroke includes current evidence-based recommendations and …

Integrated care for optimizing the management of stroke and associated heart disease: a position paper of the European Society of Cardiology Council on Stroke

GYH Lip, DA Lane, R Lenarczyk, G Boriani… - European Heart …, 2022 - academic.oup.com
The management of patients with stroke is often multidisciplinary, involving various
specialties and healthcare professionals. Given the common shared risk factors for stroke …

Large vessel occlusion stroke due to intracranial atherosclerotic disease: identification, medical and interventional treatment, and outcomes

A De Havenon, OO Zaidat, S Amin-Hanjani… - Stroke, 2023 - Am Heart Assoc
Large vessel occlusion stroke due to underlying intracranial atherosclerotic disease (ICAD-
LVO) is prevalent in 10 to 30% of LVOs depending on patient factors such as vascular risk …

Genetic polymorphisms and clopidogrel efficacy for acute ischemic stroke or transient ischemic attack: a systematic review and meta-analysis

Y Pan, W Chen, Y Xu, X Yi, Y Han, Q Yang, X Li… - Circulation, 2017 - Am Heart Assoc
Background: The association of genetic polymorphisms and clopidogrel efficacy in patients
with ischemic stroke or transient ischemic attack (TIA) remains controversial. We performed …

Pharmacogenetics to guide cardiovascular drug therapy

JD Duarte, LH Cavallari - Nature Reviews Cardiology, 2021 - nature.com
Over the past decade, pharmacogenetic testing has emerged in clinical practice to guide
selected cardiovascular therapies. The most common implementation in practice is …