Centromeres are the chromosomal domains required to ensure faithful transmission of the
genome during cell division. They have a central role in preventing aneuploidy, by …

Chromosomal abnormalities, consisting of numerical and structural chromosome
abnormalities, are a common characteristic of cancer. Numerical chromosome …

Breast cancer is a common and threatening malignant disease with multiple biological and
clinical subtypes. It can be categorized into subtypes of luminal A, luminal B, Her2 positive …

Hepatocellular carcinoma (HCC) is the most common cancer in the world especially in East
Asia and Africa. Advanced stage, metastasis and frequent relapse are responsible for the …

Male breast cancer (MBC) is extremely rare and accounts for less than 1% of all breast
malignancies. Therefore, clinical management of MBC is currently guided by research on …

Introduction Compared with breast cancer (BC) in women, BC in men is a rare disease with
genetic and molecular peculiarities. Therapeutic approaches for male BC (MBC) are …

The factors involved in cell differentiation have recently garnered interest for their role in
inhibition of pathogenesis in various tumors. However, their role in glioblastoma (GBM) …

Simple Summary Triple-negative breast cancer (TNBC) comprises about 15% of all breast
cancers worldwide and is known to have a poorer prognosis compared to other subtypes of …

HER2 receptor is overexpressed approximately in 20% of human breast cancer (BC) and is
a poor prognostic factor. Although therapies targeting this receptor have improved the …

The growth factor receptor bound protein 7 (Grb7) is an adaptor protein that is often
coamplified with the erythroblastosis oncogene B 2 receptor in 20% to 30% of breast cancer …