Artificial intelligence in cancer imaging: clinical challenges and applications
Judgement, as one of the core tenets of medicine, relies upon the integration of multilayered
data with nuanced decision making. Cancer offers a unique context for medical decisions …
data with nuanced decision making. Cancer offers a unique context for medical decisions …
Consensus recommendations for a standardized brain tumor imaging protocol for clinical trials in brain metastases
A recent meeting was held on March 22, 2019, among the FDA, clinical scientists,
pharmaceutical and biotech companies, clinical trials cooperative groups, and patient …
pharmaceutical and biotech companies, clinical trials cooperative groups, and patient …
Safety of combining radiotherapy with immune-checkpoint inhibition
Immune-checkpoint inhibitors targeting cytotoxic T-lymphocyte antigen 4 (CTLA-4),
programmed cell death protein 1 (PD-1), or programmed cell death 1 ligand 1 (PD-L1) have …
programmed cell death protein 1 (PD-1), or programmed cell death 1 ligand 1 (PD-L1) have …
[HTML][HTML] Diagnosis and management of radiation necrosis in patients with brain metastases
The use of radiotherapy, either in the form of stereotactic radiosurgery (SRS) or whole-brain
radiotherapy (WBRT), remains the cornerstone for the treatment of brain metastases (BM) …
radiotherapy (WBRT), remains the cornerstone for the treatment of brain metastases (BM) …
Brain metastases: neuroimaging
WB Pope - Handbook of clinical neurology, 2018 - Elsevier
Magnetic resonance imaging (MRI) is the cornerstone for evaluating patients with brain
masses such as primary and metastatic tumors. Important challenges in effectively detecting …
masses such as primary and metastatic tumors. Important challenges in effectively detecting …
[HTML][HTML] Mechanisms and therapy for cancer metastasis to the brain
F Franchino, R Rudà, R Soffietti - Frontiers in oncology, 2018 - frontiersin.org
Advances in chemotherapy and targeted therapies have improved survival in cancer
patients with an increase of the incidence of newly diagnosed brain metastases (BMs) …
patients with an increase of the incidence of newly diagnosed brain metastases (BMs) …
Differentiation between radiation necrosis and tumor progression using chemical exchange saturation transfer
Purpose: Stereotactic radiosurgery (SRS) is a common treatment used in patients with brain
metastases and is associated with high rates of local control, however, at the risk of radiation …
metastases and is associated with high rates of local control, however, at the risk of radiation …
Distinguishing true progression from radionecrosis after stereotactic radiation therapy for brain metastases with machine learning and radiomics
Purpose Treatment effect or radiation necrosis after stereotactic radiosurgery (SRS) for brain
metastases is a common phenomenon often indistinguishable from true progression …
metastases is a common phenomenon often indistinguishable from true progression …
[HTML][HTML] Combined FET PET/MRI radiomics differentiates radiation injury from recurrent brain metastasis
P Lohmann, M Kocher, G Ceccon, EK Bauer… - NeuroImage: Clinical, 2018 - Elsevier
Background The aim of this study was to investigate the potential of combined textural
feature analysis of contrast-enhanced MRI (CE-MRI) and static O-(2-[18 F] fluoroethyl)-L …
feature analysis of contrast-enhanced MRI (CE-MRI) and static O-(2-[18 F] fluoroethyl)-L …
Dynamic O-(2-18F-fluoroethyl)-L-tyrosine positron emission tomography differentiates brain metastasis recurrence from radiation injury after radiotherapy
G Ceccon, P Lohmann, G Stoffels, N Judov… - Neuro …, 2017 - academic.oup.com
Background The aim of this study was to investigate the potential of dynamic O-(2-[18F]
fluoroethyl)-L-tyrosine (18F-FET) PET for differentiating local recurrent brain metastasis from …
fluoroethyl)-L-tyrosine (18F-FET) PET for differentiating local recurrent brain metastasis from …