[HTML][HTML] Growth hormone in fertility and infertility: Mechanisms of action and clinical applications

CW Chang, YW Sung, YW Hsueh, YY Chen… - Frontiers in …, 2022 - frontiersin.org
Secreted by the anterior pituitary gland, growth hormone (GH) is a peptide that plays a
critical role in regulating cell growth, development, and metabolism in multiple targeted …

Administration of growth hormone improves endometrial function in women undergoing in vitro fertilization: a systematic review and meta-analysis

Y Shang, M Wu, R He, Y Ye… - Human Reproduction …, 2022 - academic.oup.com
BACKGROUND The positive effects of growth hormone (GH) on IVF are often attributed to
improvements in oocyte and embryo quality. While emerging evidence emphasizes GH …

[HTML][HTML] Growth hormone reduces aneuploidy and improves oocytes quality by JAK2-MAPK3/1 pathway in aged mice

YY Luo, X Zeng, L Zhu, C Li, J Xie, Q Dong… - Journal of Translational …, 2023 - Springer
Background The global delay in women's reproductive age has raised concerns about age-
related infertility. The decline in oocyte quality is a limiting factor of female fertility, yet there …

[HTML][HTML] The clinical application of growth hormone and its biological and molecular mechanisms in assisted reproduction

P Pan, X Huang - International Journal Of Molecular Sciences, 2022 - mdpi.com
Growth hormone (GH) has been used as a co-gonadotrophin in assisted reproduction,
particularly in poor ovarian responders. The application of GH has been alleged to activate …

Metabolic hormones are integral regulators of female reproductive health and function

F Athar, M Karmani, NM Templeman - Bioscience Reports, 2024 - portlandpress.com
The female reproductive system is strongly influenced by nutrition and energy balance. It is
well known that food restriction or energy depletion can induce suppression of reproductive …

[HTML][HTML] Stimulation for low responder patients: adjuvants during stimulation

RJ Hart - Fertility and Sterility, 2022 - Elsevier
Growth hormone, letrozole, and clomiphene citrate do not have US Food and Drug
Administration approval for their use in in vitro fertilization (IVF) cycles. However, despite this …

Growth hormone for in vitro fertilisation (IVF)

A Sood, G Mohiyiddeen, G Ahmad… - Cochrane Database …, 2021 - cochranelibrary.com
Background In an effort to improve outcomes of in vitro fertilisation (IVF) cycles, the use of
growth hormone (GH) has been considered as adjuvant treatment in ovarian stimulation …

[HTML][HTML] Calcium ionophore improves embryonic development and pregnancy outcomes in patients with previous developmental problems in ICSI cycles

X Chen, H Zhao, J Lv, Y Dong, M Zhao, X Sui… - BMC Pregnancy and …, 2022 - Springer
Abstract Background Calcium (Ca2+) ionophores are now mainly considered as efficient
treatments for fertilization failure. Recently, its application for rescuing poor embryo …

[HTML][HTML] Impact of Follicle Stimulating Hormone Receptor (FSHR) Polymorphism on the Efficiency of Co-Treatment with Growth Hormone in a Group of Infertile Women …

M Surcel, B Doroftei, IA Neamtiu, D Muresan… - Diagnostics, 2022 - mdpi.com
“Poor responders”(PR) are an important category of infertile women who experience a
modest response to controlled ovarian stimulation. In this study, we evaluated response to …

[HTML][HTML] Does growth hormone supplementation of in vitro fertilization/intracytoplasmic sperm injection improve cumulative live birth rates in women with poor …

X Liu, N Li, D Wang, W Wen, L Tian, H Zhou… - Reproductive Biology …, 2024 - Springer
Background Growth hormone (GH) has been proposed as an adjunct in in vitro fertilization
(IVF)/intracytoplasmic sperm injection (ICSI) cycles, especially in women with poor ovarian …