Transdermal devices are used to deliver drugs through the skin. However, limitations such
as molecular weight and hydrophilicity of the molecules prevent its wider use. Microneedle …

Chronic diseases (CDs) are noncommunicable illnesses with long-term symptoms
accounting for~ 70% of all deaths worldwide. For the diagnosis and prognosis of CDs …

The resection of malignant osteosarcoma often results in large segmental bone defects, and
the residual cells can facilitate recurrence. Consequently, the treatment of osteosarcoma is a …

Microelectromechanical system (MEMS)-based microneedles are an innovative way of drug
delivery that increases the permeability of the skin. It generates microscopic pores inside the …

Injectable hydrogels are of great interest in tissue engineering, and those incorporating
hydroxyapatite (HA) are especially acclaimed in the application of bone repair. Synthetic …

The natural polysaccharide/hydroxyapatite hydrogels are of great interest to bone tissue
engineering, but the interfacial mismatch between rigid hydroxyapatite and soft …

Biomolecules-mediated biomimetic mineralization has been extensively investigated and
applied to fabricate nano-assemblies with unique hierarchical architectures and salient …

In recent years, microneedles (MNs) have emerged as a promising alternative to traditional
drug delivery systems in transdermal drug delivery. The use of MNs has demonstrated …

One of the most cutting-edge, effective, and least invasive pharmaceutical innovations is the
utilization of microneedles (MNs) for drug delivery, patient monitoring, diagnostics, medicine …

During the past decades, the advent of different microneedle patch (MNPs) systems paves
the way for the targeted and efficient delivery of several growth factors into the injured sites …