Consensus guidelines for the use and interpretation of angiogenesis assays
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …
important roles in growth and development, tissue and organ regeneration, as well as …
Selenium species: current status and potentials in cancer prevention and therapy
HW Tan, HY Mo, ATY Lau, YM Xu - International journal of molecular …, 2018 - mdpi.com
Selenium (Se) acts as an essential trace element in the human body due to its unique
biological functions, particularly in the oxidation-reduction system. Although several clinical …
biological functions, particularly in the oxidation-reduction system. Although several clinical …
Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model
M Cafora, G Deflorian, F Forti, L Ferrari, G Binelli… - Scientific reports, 2019 - nature.com
Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes
mortality in humans mainly due to respiratory infections caused by Pseudomonas …
mortality in humans mainly due to respiratory infections caused by Pseudomonas …
Recent considerations in the application of RAPTA‐C for cancer treatment and perspectives for its combination with immunotherapies
M Rausch, PJ Dyson… - Advanced …, 2019 - Wiley Online Library
The organometallic ruthenium (II)[Ru (arene) Cl2PTA] PTA‐1, 3, 5‐triaza‐7‐
phosphaadamantane compound, RAPTA‐C, represents an innovative anti‐cancer …
phosphaadamantane compound, RAPTA‐C, represents an innovative anti‐cancer …
WTAP activates MAPK signaling through m6A methylation in VEGFA mRNA‐mediated by YTHDC1 to promote colorectal cancer development
M Ye, J Chen, P Yu, C Hu, B Wang, J Bao… - The FASEB …, 2023 - Wiley Online Library
N6‐methyladenosine modification, especially Wilms tumor 1‐associated protein (WTAP), is
reportedly associated with a variety of cancers, including colorectal cancer (CRC) …
reportedly associated with a variety of cancers, including colorectal cancer (CRC) …
miRNAs: micro-managers of anticancer combination therapies
JR van Beijnum, E Giovannetti, D Poel… - Angiogenesis, 2017 - Springer
Angiogenesis is one of the hallmarks of cancer progression and as such has been
considered a target of therapeutic interest. However, single targeted agents have not fully …
considered a target of therapeutic interest. However, single targeted agents have not fully …
Advances in the discovery of microRNA-based anticancer therapeutics: latest tools and developments
KKW To, W Fong, CWS Tong, M Wu… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: MicroRNAs (miRNAs) are small endogenous non-coding RNAs that repress the
expression of their target genes by reducing mRNA stability and/or inhibiting translation …
expression of their target genes by reducing mRNA stability and/or inhibiting translation …
Epigenetic drugs as new emerging therapeutics: What is the scale's orientation of application and challenges?
Epigenetics is the study of heritable changes in gene expression or function without altering
the DNA sequence. Important factors are part of epigenetic events, such as methylation …
the DNA sequence. Important factors are part of epigenetic events, such as methylation …
Translational research on drug development and biomarker discovery for hepatocellular carcinoma
Translational research plays a key role in drug development and biomarker discovery for
hepatocellular carcinoma (HCC). However, unique challenges exist in this field because of …
hepatocellular carcinoma (HCC). However, unique challenges exist in this field because of …
Optimized combination of HDACI and TKI efficiently inhibits metabolic activity in renal cell carcinoma and overcomes sunitinib resistance
M Rausch, A Weiss, M Zoetemelk, SR Piersma… - Cancers, 2020 - mdpi.com
Simple Summary To ameliorate the situation for kidney cancer patients and to broaden the
application of available drugs, we initiated this research to enhance the anti-cancer activity …
application of available drugs, we initiated this research to enhance the anti-cancer activity …