Consensus guidelines for the use and interpretation of angiogenesis assays

P Nowak-Sliwinska, K Alitalo, E Allen, A Anisimov… - Angiogenesis, 2018 - Springer
The formation of new blood vessels, or angiogenesis, is a complex process that plays
important roles in growth and development, tissue and organ regeneration, as well as …

Selenium species: current status and potentials in cancer prevention and therapy

HW Tan, HY Mo, ATY Lau, YM Xu - International journal of molecular …, 2018 - mdpi.com
Selenium (Se) acts as an essential trace element in the human body due to its unique
biological functions, particularly in the oxidation-reduction system. Although several clinical …

Phage therapy against Pseudomonas aeruginosa infections in a cystic fibrosis zebrafish model

M Cafora, G Deflorian, F Forti, L Ferrari, G Binelli… - Scientific reports, 2019 - nature.com
Cystic fibrosis (CF) is a hereditary disease due to mutations in the CFTR gene and causes
mortality in humans mainly due to respiratory infections caused by Pseudomonas …

Recent considerations in the application of RAPTA‐C for cancer treatment and perspectives for its combination with immunotherapies

M Rausch, PJ Dyson… - Advanced …, 2019 - Wiley Online Library
The organometallic ruthenium (II)[Ru (arene) Cl2PTA] PTA‐1, 3, 5‐triaza‐7‐
phosphaadamantane compound, RAPTA‐C, represents an innovative anti‐cancer …

WTAP activates MAPK signaling through m6A methylation in VEGFA mRNA‐mediated by YTHDC1 to promote colorectal cancer development

M Ye, J Chen, P Yu, C Hu, B Wang, J Bao… - The FASEB …, 2023 - Wiley Online Library
N6‐methyladenosine modification, especially Wilms tumor 1‐associated protein (WTAP), is
reportedly associated with a variety of cancers, including colorectal cancer (CRC) …

miRNAs: micro-managers of anticancer combination therapies

JR van Beijnum, E Giovannetti, D Poel… - Angiogenesis, 2017 - Springer
Angiogenesis is one of the hallmarks of cancer progression and as such has been
considered a target of therapeutic interest. However, single targeted agents have not fully …

Advances in the discovery of microRNA-based anticancer therapeutics: latest tools and developments

KKW To, W Fong, CWS Tong, M Wu… - Expert opinion on …, 2020 - Taylor & Francis
Introduction: MicroRNAs (miRNAs) are small endogenous non-coding RNAs that repress the
expression of their target genes by reducing mRNA stability and/or inhibiting translation …

Epigenetic drugs as new emerging therapeutics: What is the scale's orientation of application and challenges?

MR Farani, M Sarlak, A Gholami, M Azaraian… - … -Research and Practice, 2023 - Elsevier
Epigenetics is the study of heritable changes in gene expression or function without altering
the DNA sequence. Important factors are part of epigenetic events, such as methylation …

Translational research on drug development and biomarker discovery for hepatocellular carcinoma

V Chew, CH Chuang, C Hsu - Journal of Biomedical Science, 2024 - Springer
Translational research plays a key role in drug development and biomarker discovery for
hepatocellular carcinoma (HCC). However, unique challenges exist in this field because of …

Optimized combination of HDACI and TKI efficiently inhibits metabolic activity in renal cell carcinoma and overcomes sunitinib resistance

M Rausch, A Weiss, M Zoetemelk, SR Piersma… - Cancers, 2020 - mdpi.com
Simple Summary To ameliorate the situation for kidney cancer patients and to broaden the
application of available drugs, we initiated this research to enhance the anti-cancer activity …