Membranous nephropathy: systems biology-based novel mechanism and traditional Chinese medicine therapy

H Miao, Y Zhang, X Yu, L Zou, Y Zhao - Frontiers in pharmacology, 2022 - frontiersin.org
Membranous nephropathy (MN) is a renal-limited non-inflammatory autoimmune disease in
the glomerulus, which is the second or third main cause of end-stage kidney diseases in …

Urinary podocyte markers in kidney diseases

L Zeng, CC Szeto - Clinica Chimica Acta, 2021 - Elsevier
Podocytes play an important role in the maintenance of kidney function, and they are the
primary focus of many kidney diseases. Podocyte injury results in the shedding of podocyte …

Curcumin improves the renal autophagy in rat experimental membranous nephropathy via regulating the PI3K/AKT/mTOR and Nrf2/HO‐1 signaling pathways

Q Di Tu, J Jin, X Hu, Y Ren, L Zhao… - BioMed research …, 2020 - Wiley Online Library
Membranous nephropathy (MN, also known as membranous glomerulopathy) is one of the
many glomerular diseases causing nephrotic syndrome. The literature indicates that …

Novel biomarkers in membranous nephropathy

Q Liu, J Liu, B Lin, Y Zhang, M Ma, M Yang… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the main cause of adult nephrotic syndrome (NS). The
pathogenesis of MN is complex and involves subepithelial immune complex deposition …

Fumarate modulates phospholipase A2 receptor autoimmunity-induced podocyte injury in membranous nephropathy

HA Jo, JS Hyeon, SH Yang, Y Jung, H Ha, CW Jeong… - Kidney International, 2021 - Elsevier
Downstream mechanisms that lead to podocyte injury following phospholipase A2 receptor
(PLA2R) autoimmunity remain elusive. To help define this we compared urinary …

Crocin improves the renal autophagy in rat experimental membranous nephropathy via regulating the SIRT1/Nrf2/HO-1 signaling pathway

H Liu, H Cheng, H Wang, Q Wang, J Yuan - Renal Failure, 2023 - Taylor & Francis
Membranous nephropathy (MN) is a glomerular disease. Crocin is isolated from saffron and
gardenia. Its antioxidant, anti-inflammatory, anti-hyperlipidemic, anti-atherosclerotic, anti …

MicroRNA‑193a‑5p exerts a tumor suppressive role in epithelial ovarian cancer by modulating RBBP6

S Zhang, J Liu, J He, N Yi - Molecular Medicine …, 2021 - spandidos-publications.com
Epithelial ovarian cancer (EOC), a gynecological tumor, is associated with high mortality.
MicroRNAs (miRs) serve a crucial role in EOC; however, the mechanisms underlying the …

Serum protein signatures using aptamer-based proteomics for minimal change disease and membranous nephropathy

DA Muruve, H Debiec, ST Dillon, X Gu… - Kidney International …, 2022 - Elsevier
Introduction Minimal change disease (MCD) and membranous nephropathy (MN) are
glomerular diseases (glomerulonephritis [GN]) that present with the nephrotic syndrome …

MicroRNA193a: An Emerging Mediator of Glomerular Diseases

J Bharati, M Kumar, N Kumar, A Malhotra, PC Singhal - Biomolecules, 2023 - mdpi.com
MicroRNAs (miRNAs) are noncoding small RNAs that regulate the protein expression of
coding messenger RNAs. They are used as biomarkers to aid in diagnosing …

miR-150 inhibitor ameliorates adriamycin-induced focal segmental glomerulosclerosis

H Qi, J Fu, J Luan, C Jiao, X Cui, X Cao… - Biochemical and …, 2020 - Elsevier
Focal segmental glomerulosclerosis (FSGS) is the most common cause of adult nephrotic
syndrome in USA. Its mechanisms remain unclear and the effective treatment lacks. We …