[HTML][HTML] Solidification and oral delivery of biologics to the colon-a review

KT Kopp, L Saerens, J Voorspoels… - European Journal of …, 2023 - Elsevier
The oral delivery of biologics such as therapeutic proteins, peptides and oligonucleotides for
the treatment of colon related diseases has been the focus of increasing attention over the …

Contemporary Review on Solubility Enhancement Techniques

I Narmada - Journal of Drug Delivery and Therapeutics, 2023 - jddtonline.info
The limited water solubility of pharmacoactive molecules hinders their ability to be used as
pharmacological agents, yet the indispensability of a certain solubility parameter precludes …

The impact of applying an additional polymer coating on high drug-loaded amorphous solid dispersions layered onto pellets

E Boel, G Van den Mooter - International Journal of Pharmaceutics, 2023 - Elsevier
Inhibiting surface crystallization is an interesting strategy to enhance the physical stability of
amorphous solid dispersions (ASDs), still preserving high drug loads. The aim of this study …

A review of various manufacturing approaches for developing amorphous solid dispersions

KK Konda, S Dhoppalapudi - Journal of Drug Delivery and …, 2022 - jddtonline.info
In recent years amorphous solid dispersions (ASD) has gained a tremendous response for
improving the solubility of poorly water-soluble drug substances. Despite the stability …

A review of hot melt extrusion paired fused deposition modeling three-dimensional printing for developing patient centric dosage forms

S Dhoppalapudi, N Illa - GSC Biological and Pharmaceutical …, 2022 - gsconlinepress.com
In recent years, the demand for developing patient-centric dosage forms is increasing
enormously with the increasing patient population. Much research is ongoing exploring …

[PDF][PDF] Investigation of bead coating as manufacturing process for the development of amorphous solid dispersions

E Boel - 2023 - lirias.kuleuven.be
The number of drug molecules that show poor aqueous solubility and low dissolution rate
has significantly increased during the past two decades, resulting in low oral bioavailability …