Neurodevelopmental effects of insulin-like growth factor signaling

J O'Kusky, P Ye - Frontiers in neuroendocrinology, 2012 - Elsevier
Insulin-like growth factor (IGF) signaling greatly impacts the development and growth of the
central nervous system (CNS). IGF-I and IGF-II, two ligands of the IGF system, exert a wide …

Leptin: a hormone linking activation of neuroendocrine axes with neuropathology

MR Stieg, C Sievers, O Farr, GK Stalla… - …, 2015 - Elsevier
Leptin, a peptide hormone secreted by adipocytes, plays a central role in controlling appetite
and weight in both rodents and humans. Basic science and clinical research suggest that …

[HTML][HTML] A 20-week program of resistance or concurrent exercise improves symptoms of schizophrenia: results of a blind, randomized controlled trial

B Andrade e Silva, RC Cassilhas, C Attux… - Brazilian Journal of …, 2015 - SciELO Brasil
Objective: To evaluate the effects of 20 weeks of resistance and concurrent training on
psychotic and depressive symptoms, quality of life outcomes, and serum IGF-1, IGFBP-3 …

Cytokine and adipokine alterations in patients with schizophrenia treated with clozapine

JP Klemettilä, O Kampman, N Seppälä, M Viikki… - Psychiatry …, 2014 - Elsevier
Metabolic syndrome is associated with both schizophrenia and antipsychotic medication,
especially clozapine, with alterations in inflammatory cytokines and adipokines. However …

Evaluation of IGF-1 as a novel theranostic biomarker for schizophrenia

UH Yesilkaya, S Gica, MC Ilnem, M Sen… - Journal of Psychiatric …, 2021 - Elsevier
Objective In the current study, we aimed to investigate fasting plasma levels of glucose,
insulin, growth hormone, IGF-1, and lipid profile in remission schizophrenia patients …

S100B serum levels in schizophrenia are presumably related to visceral obesity and insulin resistance

J Steiner, AM Myint, K Schiltz… - Cardiovascular …, 2010 - Wiley Online Library
Elevated blood levels of S100B in schizophrenia have so far been mainly attributed to glial
pathology, as S100B is produced by astro‐and oligodendroglial cells and is thought to act …

A cross-sectional evaluation of adiponectin plasma levels in patients with schizophrenia and schizoaffective disorder

L Hanssens, R van Winkel, M Wampers… - Schizophrenia …, 2008 - Elsevier
BACKGROUND: In recent years, several studies showed increased rates of hyperglycaemia,
diabetes, dyslipidemia, metabolic syndrome as well as cardiovascular disease in …

Role of food-drug interactions in neurological and psychological diseases

M Gezmen Karadağ, E Çelik, F Kadayifci… - Acta neurobiologiae …, 2018 - avesis.gazi.edu.tr
Given that foods and nutrients have been shown to influence the pharmacokinetics of drugs,
drugs may cause changes in the nutritional status of patients and their response to a given …

Obesity, cardiovascular disease and type 2 diabetes in people with a mental illness: a need for primary health care

SH Stanley, JDE Laugharne - Australian Journal of Primary …, 2012 - CSIRO Publishing
People with a mental illness show a growing incidence of obesity, and higher rates of
metabolic syndrome when compared with the general population. This paper reviews …

Association between serum insulin-like growth factor 1 levels and the improvements of cognitive impairments in a subgroup of schizophrenia: Preliminary findings

J Xiong, Y Ding, X Wu, J Zhan, Q Wan, H Wan… - Schizophrenia …, 2024 - Elsevier
Background Numerous studies have implicated abnormal insulin-like growth factor 1 (IGF-1)
in the pathophysiology of schizophrenia, but findings have been inconsistent. Methods We …