Physical activity measurements in individuals with interstitial lung disease: a systematic review and meta-analysis

M Iwakura, A Kawagoshi, A Tamaki… - European …, 2023 - Eur Respiratory Soc
Background Physical activity (PA) measurements are becoming common in interstitial lung
disease (ILD); however, standardisation has not been achieved. We aimed to systematically …

Phase angle in assessment and monitoring treatment of individuals with respiratory disease

F De Benedetto, S Marinari, F De Blasio - Reviews in Endocrine and …, 2023 - Springer
Phase angle (PhA) represents a raw variable measured with bioelectrical impedance
analysis (BIA) that is used to assess malnutrition in many diseases, including respiratory …

[HTML][HTML] Endocrine and metabolic factors and the risk of idiopathic pulmonary fibrosis: a mendelian randomization study

Y Jiang, R Chen, S Xu, Y Ding, M Zhang… - Frontiers in …, 2024 - frontiersin.org
Background: Previous observational studies have investigated the association between
endocrine and metabolic factors and idiopathic pulmonary fibrosis (IPF), yet have produced …

Preclinical studies in Krabbe disease: A model for the investigation of novel combination therapies for lysosomal storage diseases

G Heller, AM Bradbury, MS Sands, ER Bongarzone - Molecular Therapy, 2023 - cell.com
Krabbe disease (KD) is a lysosomal storage disease (LSD) caused by mutations in the galc
gene. There are over 50 monogenetic LSDs, which largely impede the normal development …

Sarcopenia in idiopathic pulmonary fibrosis: a prospective study exploring prevalence, associated factors and diagnostic approach

P Faverio, A Fumagalli, S Conti, F Madotto, F Bini… - Respiratory …, 2022 - Springer
Background Sarcopenia gained importance in the evaluation of patients with chronic
respiratory diseases, including idiopathic pulmonary fibrosis (IPF), since it may impact …

Frequency and impact on clinical outcomes of sarcopenia in patients with idiopathic pulmonary fibrosis

K Fujita, H Ohkubo, A Nakano, Y Mori… - Chronic Respiratory …, 2022 - journals.sagepub.com
Objectives Sarcopenia is a syndrome characterized by reduced muscle mass and function. It
is well-recognized as a complication in chronic diseases such as chronic obstructive …

Observational, multicenter study on the efficacy, tolerability, and safety of Nintedanib in patients with idiopathic pulmonary fibrosis older than 80 years

M Mondoni, F Alfano, F Varone, G Muscato, C Conti… - Respiration, 2023 - karger.com
Background: Idiopathic pulmonary fibrosis (IPF) primarily affects old patients. Old age is a
predictor of mortality. Nintedanib, the only antifibrotic drug approved in Italy for patients …

Vitamin D and idiopathic pulmonary fibrosis: a two-sample mendelian randomization study

T Lin, F Zhou, H Mao, Z Xie, Y Jin - BMC Pulmonary Medicine, 2023 - Springer
Background A prospective study of multiple small samples found that idiopathic pulmonary
fibrosis (IPF) is often accompanied by a deficiency in Vitamin D levels. However, the causal …

Antifibrotic effects of vitamin D3 on human lung fibroblasts derived from patients with idiopathic pulmonary fibrosis

T Voisin, A Joannes, C Morzadec… - The Journal of …, 2024 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease. Up to
now, no treatment can stop the progression of IPF. Vitamin D3 (VD) reduces experimental …

Fibroblast Upregulation of Vitamin D Receptor Represents a Self-Protective Response to Limit Fibroblast Proliferation and Activation during Pulmonary Fibrosis

J Wei, J Zhan, H Ji, Y Xu, Q Xu, X Zhu, Y Liu - Antioxidants, 2023 - mdpi.com
Dysregulation of vitamin D receptor (VDR) is implicated in chronic obstructive pulmonary
disease. However, whether VDR dysregulation contributes to the development of pulmonary …