Pharmacology and Therapeutic Potential of the 5-HT7 Receptor
KM Blattner, DJ Canney, DA Pippin… - ACS Chemical …, 2018 - ACS Publications
It is well-documented that serotonin (5-HT) exerts its pharmacological effects through a
series of 5-HT receptors. The most recently identified member of this family, 5-HT7, was first …
series of 5-HT receptors. The most recently identified member of this family, 5-HT7, was first …
Outstanding animal studies in allergy I. From asthma to food allergy and anaphylaxis
E Jensen-Jarolim, I Pali-Schöll… - Current opinion in …, 2017 - journals.lww.com
Natural and artificial animal models were used to explore the pathophysiology of asthma,
food allergy and anaphylaxis and to improve prophylactic and therapeutic measures …
food allergy and anaphylaxis and to improve prophylactic and therapeutic measures …
5-HT7 Receptor Contributes to Proliferation, Migration and Invasion in NSCLC Cells
X Du, T Wang, Z Wang, X Wu, Y Gu… - OncoTargets and …, 2020 - Taylor & Francis
Introduction Because only a small portion of NSCLC (non-small-cell lung cancer) patients
benefit from molecular targeted therapy or immunotherapy and do not develop therapeutic …
benefit from molecular targeted therapy or immunotherapy and do not develop therapeutic …
Mesenchymal stem cells attenuate the proinflammatory cytokine pattern in a guinea pig model of chronic cigarette smoke exposure
Aims Cigarette smoke often induces pulmonary and systemic inflammation. In animal
models, mesenchymal stem cells (MSC) tend to ameliorate these effects. We aimed to …
models, mesenchymal stem cells (MSC) tend to ameliorate these effects. We aimed to …
Effects of intranasal treatment with slow (GYY4137) and rapid (NaHS) donors of hydrogen sulfide in lipopolysaccharide-induced airway inflammation in mice
Y Kaya-Yasar, Y Karaman, TE Bozkurt… - Pulmonary …, 2017 - Elsevier
We have investigated the effects of slow (GYY4137) and rapid (NaHS) hydrogen sulfide (H 2
S) releasing donors in lipopolysaccharide (LPS)-induced airway inflammation in mice. LPS …
S) releasing donors in lipopolysaccharide (LPS)-induced airway inflammation in mice. LPS …
Role of peripheral 5-HT5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats
HT inhibits cardiac sympathetic neurotransmission in normoglycaemic rats, via 5-HT1B, 5-
HT1D and 5-HT5A receptor activation. Since type 1 diabetes impairs the cardiac …
HT1D and 5-HT5A receptor activation. Since type 1 diabetes impairs the cardiac …
Structure-activity relationships of serotonin 5-HT7 receptors ligands: A review
SL Thirumaran, A Lepailleur, C Rochais - European Journal of Medicinal …, 2019 - Elsevier
HT 7 receptors are the most recently discovered serotonergic receptors, for which numerous
physiological implications in the central and the peripheral nervous systems as well as the …
physiological implications in the central and the peripheral nervous systems as well as the …
[HTML][HTML] Allergic sensitization increases contractile responses to 5-HT in guinea pig aorta
P Campos-Bedolla, DELACN Rafael… - Physiological …, 2020 - ncbi.nlm.nih.gov
Epidemiological and clinical studies suggest that asthma is associated with adverse
cardiovascular outcomes, but its mechanism is uncertain. 5-Hydroxytryptamine (5-HT) is a …
cardiovascular outcomes, but its mechanism is uncertain. 5-Hydroxytryptamine (5-HT) is a …
[PDF][PDF] The Role of Muscarinic M2 and M3 Receptor Subtypes in Cardiopulmonary Responsiveness: Insights from In Vivo Murine Models
S Vincent - 2020 - qspace.library.queensu.ca
Muscarinic receptors play an important role in cholinergic transmission and physiologic
events. However, the study of the mechanisms by which muscarinic receptors mediate …
events. However, the study of the mechanisms by which muscarinic receptors mediate …
Exclusive Peripheral Overexpression of 5-HT5A Receptors is Involved in 5‑HT‑Induced Cardiac Sympatho-Inhibition in Type 1 Diabetic Rats
Background: In normoglycaemic pithed rats, cardiac sympathetic control is modulated by
serotonin (5-hydroxytryptamine; 5‑HT), which inhibits the cardioaccelerator sympathetic …
serotonin (5-hydroxytryptamine; 5‑HT), which inhibits the cardioaccelerator sympathetic …