Activity-based diagnostics: recent advances in the development of probes for use with diverse detection modalities

RK Muir, M Guerra, MM Bogyo - ACS Chemical Biology, 2022 - ACS Publications
Abnormal enzyme expression and activity is a hallmark of many diseases. Activity-based
diagnostics are a class of chemical probes that aim to leverage this dysregulated metabolic …

Acute myeloid leukemia: advances in diagnosis and classification

RP Hasserjian - International journal of laboratory hematology, 2013 - Wiley Online Library
Acute myeloid leukemia is an aggressive myeloid neoplasm characterized by≥ 20%
myeloblasts in the blood or bone marrow. Current treatment strategies for acute myeloid …

[PDF][PDF] Guidelines on the use of multicolour flow cytometry in the diagnosis of haematological neoplasms.

U Johansson, D Bloxham, S Couzens… - British journal of …, 2014 - researchgate.net
1University Hospitals Bristol NHS Foundation Trust, Bristol, 2Cambridge University
Hospitals NHS Foundation Trust, Cambridge, 3University Hospital of Wales, Cardiff …

[HTML][HTML] Use of flow cytometry in clinical practice

DM Betters - Journal of the advanced practitioner in oncology, 2015 - ncbi.nlm.nih.gov
Mrs. K is a 63-year-old woman who presented to the clinic with complaints of fatigue,
bruising, weight loss of 20 pounds in the past 2 months, and decreased appetite. She stated …

[HTML][HTML] Spectrum and immunophenotypic profile of acute leukemia: a tertiary center flow cytometry experience

N Gupta, R Pawar, S Banerjee, S Brahma… - … journal of hematology …, 2019 - ncbi.nlm.nih.gov
Spectrum and Immunophenotypic Profile of Acute Leukemia: A Tertiary Center Flow Cytometry
Experience - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Usefulness of CD11a and CD18 in flow cytometric immunophenotypic analysis for diagnosis of acute promyelocytic leukemia

Y Zhou, JL Jorgensen, SA Wang… - American journal of …, 2012 - academic.oup.com
Acute promyelocytic leukemia (APL) is an aggressive disease that requires prompt
diagnosis and therapy. Flow cytometry immunophenotyping can serve as a screening test …

Automated deep learning-based diagnosis and molecular characterization of acute myeloid leukemia using flow cytometry

JE Lewis, LAD Cooper, DL Jaye, O Pozdnyakova - Modern Pathology, 2024 - Elsevier
The current flow cytometric analysis of blood and bone marrow samples for diagnosis of
acute myeloid leukemia (AML) relies heavily on manual intervention in the processing and …

Immunophenotypes and immune markers associated with acute promyelocytic leukemia prognosis

F Xu, CX Yin, CL Wang, XJ Jiang, L Jiang… - Disease …, 2014 - Wiley Online Library
CD2+, CD34+, and CD56+ immunophenotypes are associated with poor prognoses of acute
promyelocytic leukemia (APL). The present study aimed to explore the role of APL …

Radar plots facilitate differential diagnosis of acute promyelocytic leukemia and NPM1+ acute myeloid leukemia by flow cytometry

M Gupta, K Jafari, A Rajab, C Wei… - Cytometry Part B …, 2021 - Wiley Online Library
Background Acute promyelocytic leukemia (APL) is one of the most life‐threatening
hematological emergencies and requires a prompt correct diagnosis by cytomorphology and …

Acute myeloid leukemia with recurrent cytogenetic abnormalities

K Foucar, J Anastasi - American Journal of Clinical Pathology, 2015 - academic.oup.com
Abstract Objectives: Session 1 of the 2013 Society for Hematopathology/European
Association for Hematopathology Workshop was devoted to the cases of acute myeloid …