Human brown adipose tissue and metabolic health: potential for therapeutic avenues

R Singh, A Barrios, G Dirakvand, S Pervin - Cells, 2021 - mdpi.com
Obesity-associated metabolic abnormalities comprise a cluster of conditions including
dyslipidemia, insulin resistance, diabetes and cardiovascular diseases that has affected …

Physical activity ameliorates the function of organs via adipose tissue in metabolic diseases

N Abedpoor, F Taghian, F Hajibabaie - Acta histochemica, 2022 - Elsevier
Adipose tissue is a dynamic organ in the endocrine system that can connect organs by
secreting molecules and bioactive. Hence, adipose tissue really plays a pivotal role in …

Batokines: mediators of inter-tissue communication (a mini-review)

FT Yang, KI Stanford - Current obesity reports, 2022 - Springer
Abstract Purpose of Review This review highlights aspects of brown adipose tissue (BAT)
communication with other organ systems and how BAT-to-tissue cross-talk could help …

The role of exercise, diet, and cytokines in preventing obesity and improving adipose tissue

MM Atakan, ŞN Koşar, Y Güzel, HT Tin, X Yan - Nutrients, 2021 - mdpi.com
The prevalence of obesity continues to rise worldwide despite evidence-based public health
recommendations. The promise to adopt a healthy lifestyle is increasingly important for …

Time of day determines postexercise metabolism in mouse adipose tissue

LA Pendergrast, LS Lundell… - Proceedings of the …, 2023 - National Acad Sciences
The circadian clock is a cell-autonomous transcription–translation feedback mechanism that
anticipates and adapts physiology and behavior to different phases of the day. A variety of …

Chrononutrition—when we eat is of the essence in tackling obesity

MK Ahluwalia - Nutrients, 2022 - mdpi.com
Obesity is a chronic and relapsing public health problem with an extensive list of associated
comorbidities. The worldwide prevalence of obesity has nearly tripled over the last five …

Thermogenic adipose tissue in energy regulation and metabolic health

S Xue, D Lee, DC Berry - Frontiers in endocrinology, 2023 - frontiersin.org
The ability to generate thermogenic fat could be a targeted therapy to thwart obesity and
improve metabolic health. Brown and beige adipocytes are two types of thermogenic fat …

New insights into molecular mechanisms mediating adaptation to exercise; A review focusing on mitochondrial biogenesis, mitochondrial function, mitophagy and …

FL Roberts, GR Markby - Cells, 2021 - mdpi.com
Exercise itself is fundamental for good health, and when practiced regularly confers a myriad
of metabolic benefits in a range of tissues. These benefits are mediated by a range of …

The mitochondrial multi-omic response to exercise training across rat tissues

D Amar, NR Gay, D Jimenez-Morales, PMJ Beltran… - Cell Metabolism, 2024 - cell.com
Mitochondria have diverse functions critical to whole-body metabolic homeostasis.
Endurance training alters mitochondrial activity, but systematic characterization of these …

Cellular and molecular regulation of exercise—A neuronal perspective

I Reddy, Y Yadav, CS Dey - Cellular and Molecular Neurobiology, 2023 - Springer
The beneficial effects of exercise on the proper functioning of the body have been firmly
established. Multi-systemic metabolic regulation of exercise is the consequence of …