Premature ovarian insufficiency (POI) is the loss of normal ovarian function before the age of
40 years, a condition that affects approximately 1% of women under 40 years old and 0.1 …

Reproduction involves a wide range of biological processes, including organ formation and
development, neuroendocrine regulation, hormone production, and meiosis and mitosis …

Premature ovarian insufficiency (POI) affects 1% of women and is a leading cause of
infertility. It is often considered to be a monogenic disorder, with pathogenic variants in~ 100 …

Reproductive disorders, including intrauterine adhesion (IUA), premature ovarian
insufficiency (POI), and polycystic ovary syndrome (PCOS), are great threats to female …

Premature ovarian failure (POF) is a common female reproductive disorder and
characterized by menopause, increased gonadotropin levels and estrogen deficiency before …

Reproductive aging is on the rise globally and inseparable from the entire aging process. An
extreme form of reproductive aging is premature ovarian insufficiency (POI), which to date …

This chapter covers the known effects of endocrine disrupting chemicals (EDCs) on
reproductive disorders. The EDCs represented are highly studied, including plasticizers …

Objective We explored the gut microbiome and serum metabolome alterations in patients
with premature ovarian insufficiency (POI) and the effects of hormone replacement therapy …

The transcription factor p63 guards genome integrity in the female germline, and its
mutations have been reported in patients with premature ovarian insufficiency (POI) …

In the complex and dynamic processes of replication, transcription, and translation of DNA
molecules, a large number of replication errors or damage can occur which lead to …