Imidazole and its derivatives are one of the most important and widely used heterocycles in
medicinal chemistry, natural products, and synthetic chemicals. Because of the imidazole …

Despite the availability of some drugs, there is an urgent need for effective anti-cancer
medication. It is due to various side effects and non-functionality of the present drugs; …

The emergence and worldwide spread of drug‐resistant bacteria have already posed a
serious threat to human life, creating the urgent need to develop potent and novel …

In this study, six pyrazole derivatives containing hetero atoms have been analyzed using
theoretical calculation method. The ligands were tested by HF, B3LYP and M06-2X methods …

Eco-friendly, low-cost and high-yielding synthetic route toward imidazoles and oxazoles has
been developed. 1-(4, 6-Dimethylpyrimidin-2-yl)-2-(alkylamino)-1, 5-dihydro-4 H-imidazol-4 …

Novel non-camptothecin (non-CPT) class of conformationally constrained, hitherto unknown
7, 12-dihydrodibenzo [b, h][1, 6] naphthyridine and 7H-Chromeno [3, 2-c] quinoline …

Abstract The skeletal presence of 1, 3‐azoles in a variety of bioactive natural products,
pharmacophores, and organic materials demands the derivatization of such heteroarenes …

Introduction Epigenetic enzymes can interact with a wide range of genes that actively
participate in the progression or repression of a diseased condition, as they are involved in …

Infections caused by eukaryotic organisms, such as fungi, are generally more difficult to treat
than bacterial infections. With the widespread use of antifungal drugs in humans and plants …

Balancing between safety and efficacy of cancer chemotherapeutics is achievable by relying
on internal and/or external stimuli for selective and on-demand antitumor cytotoxicity. We …