Bacterial meningitis continues to be an important disease throughout the world and can be a
life-threatening emergency if not suspected, appropriately diagnosed and managed …

Bacterial infection of the central nervous system (CNS) is a life-threatening condition with a
high mortality. Antibiotic therapy and vaccines have changed the face of bacterial CNS …

Bacterial meningitis caused by Streptococcus pneumoniae is associated with a significant
mortality rate and persisting neurologic sequelae, including sensory–motor deficits …

The outcome of bacterial meningitis critically depends on the rapid initiation of bactericidal
antibiotic therapy and adequate management of septic shock. In community-acquired …

Bacterial meningitis is associated with high mortality and morbidity rates. Bacterial
components induce an overshooting inflammatory reaction, eventually leading to brain …

In healthy individuals, infections of the central nervous system (CNS) are comparatively rare.
Based on the ability of microglial cells to phagocytose and kill pathogens and on clinical …

Bacterial meningitis due to Streptococcus pneumoniae is associated with an significant
mortality rate and persisting neurologic sequelae including sensory-motor deficits, seizures …

Introduction. Acute bacterial meningitis remains a common disease, especially in
developing countries. Although advances over the last century have improved mortality and …

Meningitis is the most serious of invasive infections caused by the Gram-positive bacterium
Streptococcus pneumoniae. Vaccines protect only against a limited number of serotypes …

Background Pneumococcal meningitis is associated with high mortality and morbidity rates.
Up to 50% of survivors show neurologic sequelae including hearing loss, cognitive …