Intrathecal drug spread

G Hocking, JAW Wildsmith - British journal of anaesthesia, 2004 - academic.oup.com
Spinal anaesthesia has the definitive advantage that profound nerve block can be produced
in a large part of the body by the relatively simple injection of a small amount of local …

Ropivacaine: an update of its use in regional anaesthesia

KJ McClellan, D Faulds - Drugs, 2000 - Springer
Ropivacaine is a long-acting, enantiomerically pure (S-enantiomer) amide local anaesthetic
with a high pK a and low lipid solubility which blocks nerve fibres involved in pain …

Safety and efficacy of postoperative epidural analgesia

RG Wheatley, SA Schug, D Watson - British Journal of …, 2001 - bjanaesthesia.org
Effective analgesia for postoperative pain relief after major surgery has been a practical
proposition with epidural administration of local anaesthetic (LA) and opioid drugs since the …

Ropivacaine: a review of its pharmacology and therapeutic use in regional anaesthesia

A Markham, D Faulds - Drugs, 1996 - Springer
Synopsis The enantiomerically pure (S-enantiomer) amide local anaesthetic drug
ropivacaine blocked nerve fibres responsible for transmission of pain (Aδ and fibres) more …

Relative potencies of bupivacaine and ropivacaine for analgesia in labour.

G Capogna, D Celleno, P Fusco… - British journal of …, 1999 - academic.oup.com
We have used the technique of randomized, double-blind sequential allocation to compare
the minimum local analgesic concentrations (MLAC) of epidural bupivacaine and …

Ropivacaine: a review of its use in regional anaesthesia and acute pain management

D Simpson, MP Curran, V Oldfield, GM Keating - Drugs, 2005 - Springer
Ropivacaine (Naropin®) is the pure S (−)-enantiomer of propivacaine, and is a long-acting
amide local anaesthetic agent, eliciting nerve block via reversible inhibition of sodium ion …

Comparative evaluation of dexmedetomidine and fentanyl for epidural analgesia in lower limb orthopedic surgeries

SJS Bajwa, V Arora, J Kaur, A Singh… - Saudi journal of …, 2011 - journals.lww.com
Methods: A total of one hundred patients of both gender aged 21-56 years, American
Society of Anaesthesiologist (ASA) physical status I and II who underwent lower limb …

Ropivacaine: a pharmacological review

TG Hansen - Expert review of neurotherapeutics, 2004 - Taylor & Francis
Ropivacaine (Naropin®, AstraZeneca) a new long-acting amide local anaesthetic agent, is a
pure S-enantiomer, with a high pKa and relatively low-lipid solubility. Since its clinical …

Epidural analgesia in the dog and cat

RS Jones - The Veterinary Journal, 2001 - Elsevier
SUMMARY A brief outline of the history of epidural analgesia is followed by a review of the
anatomy of the epidural space with particular reference to epidural block. The technique of …

Intrathecal Ropivacaine for Ambulatory Surgery  A Comparison between Intrathecal Bupivacaine and Intrathecal Ropivacaine for Knee Arthroscopy

PE Gautier, M De Kock, A Van Steenberge… - The Journal of the …, 1999 - pubs.asahq.org
Background The rationale of this study was to evaluate intrathecal ropivacaine for
ambulatory surgery. Methods One hundred fifty patients with American Society of …