Solubility measurement and thermodynamic model correlation of baclofen in 12 pure organic solvents

C Du, Y Luo, C Huang, R Li - Journal of Chemical & Engineering …, 2022 - ACS Publications
The solubility data of baclofen in 12 different pure solvents was measured at several
temperatures. The results of solubility data were correlated using the modified Apelblat …

Dissolution thermodynamic properties calculation and intermolecular interaction analysis of diacerein in different pure and mixed solvents

C Du, R Li, L Chen - The Journal of Chemical Thermodynamics, 2022 - Elsevier
The purpose of the present work is to improve the solubility of insoluble diacerein with
cosolvent. The solubility of diacerein in pure polar aprotic solvent is significantly higher than …

The interactions and thermodynamic parameters of lenvatinib mesylate in pure and mixed solvents at several temperatures

Y Chen, Z Luo, Z Ren, L Shen, R Li, L Chen… - The Journal of Chemical …, 2023 - Elsevier
The objective of the present study was to investigate the effect of solvent properties on the
solubility profile and thermodynamic dissolution properties of lenvatinib mesylate. The …

The dissolution behaviour and thermodynamic properties calculation of praziquantel in pure and mixed organic solvents

R Li, X Chen, G He, C Wu, Z Gan, Z He, J Zhao… - The Journal of Chemical …, 2020 - Elsevier
The purpose is to study the dissolution behaviour for praziquantel in different solvent. The
dissolution capacity within the temperature range from 273.15 K to 313.15 K was researched …

Solubility determination and thermodynamic properties calculation of macitentan in mixtures of ethyl acetate and alcohols

R Li, Y Jin, B Yu, Q Xu, X Chen, D Han - The Journal of Chemical …, 2021 - Elsevier
Due to macitentan (form I) is hydrophobic and has poor solubility, in this work, the solubility
of macitentan in (methanol+ ethyl acetate),(ethanol+ ethyl acetate) and (isopropanol+ ethyl …

Solid-liquid equilibrium and thermodynamic properties of dipyridamole form II in pure solvents and mixture of (N-methyl pyrrolidone+ isopropanol)

R Li, L Fu, J Zhang, W Wang, X Chen, J Zhao… - The Journal of Chemical …, 2020 - Elsevier
The solid–liquid equilibria of a poorly soluble drug namely dipyridamole were assayed to
determine solubility in pure and binary mixtures between 273.15 K and 313.15 K under …

Exploring the solubility limits of edaravone in neat solvents and binary mixtures: experimental and machine learning study

M Przybyłek, T Jeliński, M Mianowana, K Misiak… - Molecules, 2023 - mdpi.com
This study explores the edaravone solubility space encompassing both neat and binary
dissolution media. Efforts were made to reveal the inherent concentration limits of common …

The dissolution behaviour and apparent thermodynamic analysis of doxifluridine in twelve pure solvents at various temperatures

J Sha, T Ma, R Zhao, P Zhang, R Sun, G Jiang… - The Journal of Chemical …, 2020 - Elsevier
In this work, the solubility of doxifluridine in methanol, ethanol, n-propanol, n-butanol,
isobutanol, n-Pentanol, n-hexanol, n-octanol,(±)-2-ethyl-1-hexanol, acetone, dimethyl …

[PDF][PDF] Jeli nski, T.; Przybyłek, M. Intermolecular Interactions of Edaravone in Aqueous Solutions of Ethaline and Glyceline Inferred from Experiments and Quantum …

P Cysewski - Molecules, 2023 - academia.edu
Edaravone, acting as a cerebral protective agent, is administered to treat acute brain
infarction. Its poor solubility is addressed here by means of optimizing the composition of the …

Solubility Profile and Intermolecular Force Analysis of Nimesulide (Form I) in Mono-and Mixed Solvents at Several Temperatures

L Chen, L Shen, Y Chen, Z Luo, Z Ren… - Journal of Chemical & …, 2022 - ACS Publications
The solubility data of nimesulide (form I) in different mono-and mixed solvents over the
temperature range from 273.15 to 318.15 K are determined. In this work, it is further studied …