[HTML][HTML] Revisiting diagnosis and treatment of hypertrophic cardiomyopathy: current practice and novel perspectives

A Ottaviani, D Mansour, LV Molinari, K Galanti… - Journal of Clinical …, 2023 - mdpi.com
Sarcomeric hypertrophic cardiomyopathy (HCM) is a prevalent genetic disorder
characterised by left ventricular hypertrophy, myocardial disarray, and an increased risk of …

Exercise Capacity in Patients With Obstructive Hypertrophic Cardiomyopathy: SEQUOIA-HCM Baseline Characteristics and Study Design

CJ Coats, MS Maron, TP Abraham, I Olivotto, MMY Lee… - Heart Failure, 2024 - jacc.org
Patients with obstructive hypertrophic cardiomyopathy (oHCM) have increased risk of
arrhythmia, stroke, heart failure, and sudden death. Contemporary management of oHCM …

[PDF][PDF] Aficamten for symptomatic obstructive hypertrophic cardiomyopathy

MS Maron, A Masri, ME Nassif, R Barriales-Villa… - N Engl J …, 2024 - researchgate.net
BACKGROUND One of the major determinants of exercise intolerance and limiting
symptoms among patients with obstructive hypertrophic cardiomyopathy (HCM) is an …

[HTML][HTML] Proposed diagnostic criteria for arrhythmogenic cardiomyopathy: European Task Force consensus report

D Corrado, A Anastasakis, C Basso, B Bauce… - International Journal of …, 2024 - Elsevier
Arrhythmogenic cardiomyopathy (ACM) is a heart muscle disease characterized by
prominent “non-ischemic” myocardial scarring predisposing to ventricular electrical …

[HTML][HTML] CMR Mapping: The 4th-Era Revolution in Cardiac Imaging

N Carrabba, MA Amico, AI Guaricci, MC Carella… - Journal of Clinical …, 2024 - mdpi.com
Cardiac magnetic resonance (CMR) imaging has witnessed substantial progress with the
advent of parametric mapping techniques, most notably T1 and T2 mapping. These …

Inherited arrhythmias in the pediatric population: an updated overview

MV Mariani, N Pierucci, F Fanisio, D Laviola, G Silvetti… - Medicina, 2024 - mdpi.com
Pediatric cardiomyopathies (CMs) and electrical diseases constitute a heterogeneous
spectrum of disorders distinguished by structural and electrical abnormalities in the heart …

[HTML][HTML] Gene therapy in cardiology: is a cure for hypertrophic cardiomyopathy on the horizon?

ED Paratz, J Mundisugih, SJ Rowe, E Kizana… - Canadian Journal of …, 2023 - Elsevier
Hypertrophic cardiomyopathy (HCM) is the commonest genetic cardiomyopathy world-wide,
affecting approximately 1 in 500 individuals. Current therapeutic interventions comprise …

[HTML][HTML] Morphological and genetic aspects for Post-mortem diagnosis of hypertrophic cardiomyopathy: a systematic review

V Cianci, E Forzese, D Sapienza, L Cardia… - International Journal of …, 2024 - mdpi.com
Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiovascular
diseases, and it shows an autosomal dominant pattern of inheritance. HCM can be clinically …

Phenotype, outcomes and natural history of early‐stage non‐ischaemic cardiomyopathy

DJ Hammersley, RE Jones, R Owen… - European Journal of …, 2023 - Wiley Online Library
Aims To characterize the phenotype, clinical outcomes and rate of disease progression in
patients with early‐stage non‐ischaemic cardiomyopathy (early‐NICM). Methods and results …

[HTML][HTML] Myocardial fibrosis in hypertrophic cardiomyopathy: a perspective from fibroblasts

M Schlittler, PP Pramstaller, A Rossini… - International Journal of …, 2023 - mdpi.com
Hypertrophic cardiomyopathy (HCM) is the most common inherited heart disease and the
leading cause of sudden cardiac death in young people. Mutations in genes that encode …