Diabetes mellitus (DM) displays a high morbidity. The diabetic heart is susceptible to
myocardial ischemia/reperfusion (MI/R) injury. Impaired activation of prosurvival pathways …

Thiol-based redox compounds, namely thioredoxins (Trxs), glutaredoxins (Grxs) and
peroxiredoxins (Prxs), stand as a pivotal group of proteins involved in antioxidant processes …

Objective: Leptin acts as a cardiac profibrotic factor. However, the mechanisms underlying
this effect are unclear. Therefore, we sought to elucidate the mediators involved in this …

Hydrogen peroxide (H2O2) has been reported to mediate a variety of physiological and
pathological processes in living systems. In this work, a biosensor for determination of H2O2 …

Liver ischemia/reperfusion (IR) injury is a common phenomenon after liver resection and
transplantation, which often results in liver graft dysfunction such as delayed graft function …

Aerobic interval training (AIT) exerts beneficial effects on cardiovascular disease. However,
its cardioprotective mechanisms are not fully understood. The aim of the present study was …

Reactive oxygen species (ROS) are involved with progression from infarction to heart failure.
Studies show that thyroid hormones (TH) present cardioprotective effects. This study aims to …

The present study aimed to explore the contribution of mammalian target of rapamycin
(mTOR) in deoxycorticosterone acetate (DOCA) salt–induced hypertension and related …

Amine oxidase copper‐containing 3 (AOC3) is a member of the semicarbazide‐sensitive
amine oxidase enzyme family. It acts as an ectoenzyme catalysing the oxidative …

Oxidative stress alters signalling pathways for survival and cell death favouring the adverse
remodelling of postmyocardial remnant cardiomyocytes, promoting functional impairment …