There is substantial variation between individuals in the immune response to vaccination. In
this review, we provide an overview of the plethora of studies that have investigated factors …

Neonates have an immature immune system, which cannot adequately protect against
infectious diseases. Early in life, immune protection is accomplished by maternal antibodies …

This report is a compendium of all current recommendations for the prevention of measles,
rubella, congenital rubella syndrome (CRS), and mumps. The report presents the recent …

Pediatric vaccines have significantly reduced infectious disease–related infant mortality, but
as protective immunity often requires several infant vaccine doses, maternally acquired Abs …

To generate vaccine-mediated protection is a complex challenge. Currently available
vaccines have largely been developed empirically, with little or no understanding on how …

Objective To investigate the duration of the presence of maternal antibodies to measles in
infants. Design Prospective study (May 2006 to November 2008). Setting Five hospitals in …

Measles remains an important cause of child morbidity and mortality worldwide despite the
availability of a safe and efficacious vaccine. The current measles virus (MeV) vaccine was …

Neonates are particularly susceptible to infection. This vulnerability occurs despite their
responsiveness to most vaccines. However, current vaccines do not target the pathogens …

A measles outbreak occurred in New York City. All cases had prior evidence of measles
immunity. Symptoms were consistent with measles. Laboratory results indicated secondary …

Infants are born with immature immune systems, making it difficult for them to effectively
respond to the infectious pathogens encountered shortly after birth. Maternal antibody is …