Mesenchymal stromal cells (MSCs) are crucial elements in the bone marrow (BM) niche
where they provide physical support and secrete soluble factors to control and maintain …

Outcome of patients with myelodysplastic neoplasms/syndromes (MDS) is closely related to
the biology and molecular genetics of the disease as well as its status prior to allogeneic …

In this review article, I discuss anemia caused by underlying MDS, a hematologic
malignancy associated with widely varying clinical presentations, mutation patterns, and …

Background Next-generation sequencing has identified somatic mutations that are
prognostic of cancer. Patients and Methods We evaluated the incidence and prognostic …

Reduced-intensity conditioning (RIC) has been shown to have similar overall survival (OS)
but higher relapse rates compared with myeloablative (MAC) regimens in patients with …

Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal hematopoietic
neoplastic disorders most commonly occurring in the elderly population; MDS has a …

骨髓增生异常综合征(MDS) 是一组临床表现, 病理生理学及遗传学高度异质性的克隆性疾病.
其临床特征为骨髓造血细胞发育异常, 外周血中三系血细胞减少, 以及高风险向急性髓系白血病 …

Allogeneic hematopoietic stem cell transplantation (A-HSCT) remains the only curative
option for patients with myelodysplastic syndrome (MDS). We used the NUP98-HOXD13 …

Myelodysplastic syndromes (MDSs) are heterogeneous hematopoietic disorders associated
with various degrees of myelosuppression and transformation into acute leukemia …

Methodik: Alle Publikationen beruhen auf retrospektiven Datenanalysen auf der Basis des
MDS-Registers Düsseldorf (Ethikvotumnummer 3008). Statistische Analysen erfolgten …