Potential role of Schwann cells in neuropathic pain

W Zhang, S Liu, L Ming, J Yu, C Zuo, D Hu… - European Journal of …, 2023 - Elsevier
Neuropathic pain (NPP) is a common syndrome associated with most forms of cancer, which
poses a serious threat to human health. NPP may persist even after the nociceptive …

Schwann cell TRPA1 elicits reserpine‐induced fibromyalgia pain in mice

ES Brum, MFP Fialho… - British Journal of …, 2024 - Wiley Online Library
Background and Purpose Fibromyalgia is a complex clinical disorder with an unknown
aetiology, characterized by generalized pain and co‐morbid symptoms such as anxiety and …

Mechanosensitive channel of large conductance enhances the mechanical stretching-induced upregulation of glycolysis and oxidative metabolism in Schwann cells

F Shan, N Zhang, X Yao, Y Li, Z Wang, C Zhang… - Cell Communication and …, 2024 - Springer
Background Physical exercise directly stretching the peripheral nerve promotes nerve
regeneration; however, its action mechanism remains elusive. Our present study aimed to …

Inhibition of Drp1-mediated mitochondrial fission improves contrast-induced acute kidney injury by targeting the mROS-TXNIP-NLRP3 inflammasome axis

J Zhang, Q Wei, S Wu, F Wang, TL Yuan… - International …, 2024 - Elsevier
Acute kidney injury (AKI) is a critical complication known for their extremely high mortality
rate and lack of effective clinical therapy. Disorders in mitochondrial dynamics possess a …