Perspective: Concepts of printing technologies for oral film formulations

M Preis, J Breitkreutz, N Sandler - International journal of pharmaceutics, 2015 - Elsevier
Different types of printing methods have recently attracted interest as emerging technologies
for fabrication of drug delivery systems. If printing is combined with different oral film …

Mucoadhesion and mechanical assessment of oral films

S Alaei, H Omidian - European Journal of Pharmaceutical Sciences, 2021 - Elsevier
Aligned with efforts to overcome shortcomings of conventional oral dosage forms,
mucoadhesive oral thin films have been the focus of drug development. Transmucosal drug …

A focus on mucoadhesive polymers and their application in buccal dosage forms

E Russo, F Selmin, S Baldassari, CGM Gennari… - Journal of drug delivery …, 2016 - Elsevier
Mucosa of the buccal cavity is considered a convenient and easily accessible site for the
administration of drugs intended for both local and systemic delivery. Aiming to optimize the …

Additive manufacturing of personalized orodispersible warfarin films

E Sjöholm, N Sandler - International journal of pharmaceutics, 2019 - Elsevier
Warfarin is a narrow therapeutic index drug that requires personalized dosing which is
currently not achieved by the marketed products. Further, pediatric and geriatric patients …

Fabrication of mucoadhesive buccal films for local administration of ketoprofen and lidocaine hydrochloride by combining fused deposition modeling and inkjet …

GK Eleftheriadis, PK Monou, N Bouropoulos… - Journal of …, 2020 - Elsevier
In the area of developing oromucosal drug delivery systems, mucoadhesive buccal films are
the most promising formulations for either systemic or local drug delivery. The current study …

Unidirectional drug release from 3D printed mucoadhesive buccal films using FDM technology: In vitro and ex vivo evaluation

GK Eleftheriadis, C Ritzoulis, N Bouropoulos… - European Journal of …, 2019 - Elsevier
Oromucosal delivery of active pharmaceutical ingredients provides an attractive alternative
route of administration, due to avoidance of the first pass effect and improved patient …

[HTML][HTML] Mucoadhesive buccal films based on a graft co-polymer–A mucin-retentive hydrogel scaffold

JF Alopaeus, M Hellfritzsch, T Gutowski… - European Journal of …, 2020 - Elsevier
From a patient-centric perspective, oromucosal drug delivery is highly attractive due to the
ease of administration without the need of swallowing, and improved patient safety. The aim …

Oromucosal film preparations: points to consider for patient centricity and manufacturing processes

R Krampe, JC Visser, HW Frijlink… - Expert opinion on …, 2016 - Taylor & Francis
ABSTRACT Introduction: According to the European Pharmacopoeia, oromucosal films
comprise mucoadhesive buccal films and orodispersible films. Both oral dosage forms …

Mucoadhesive gelatin buccal films with propranolol hydrochloride: Evaluation of mechanical, mucoadhesive, and biopharmaceutical properties

M Jovanović, N Tomić, S Cvijić, D Stojanović, S Ibrić… - Pharmaceutics, 2021 - mdpi.com
This study processes and characterizes propranolol hydrochloride/gelatin mucoadhesive
buccal films. Two types of gelatin are used: Gelatin from porcine skin, type A (GA), and …

Oromucosal films: From patient centricity to production by printing techniques

Y Tian, M Orlu, HJ Woerdenbag, M Scarpa… - Expert opinion on …, 2019 - Taylor & Francis
Introduction: Oromucosal films, comprising mucoadhesive buccal films (MBFs) and
orodispersible films (ODFs), are considered patient-centric dosage forms. Target groups are …