Glaucoma is a heterogeneous group of disorders that progressively lead to blindness due to
loss of retinal ganglion cells and damage to the optic nerve. It is a leading cause of …

Elevation of intraocular pressure (IOP) due to therapeutic use of glucocorticoids is called
steroid-induced ocular hypertension (SIOH); this can lead to steroid-induced glaucoma …

We conducted a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,263 affected individuals (cases) and 34,877 controls from Iceland. We identified a …

Glaucoma is the major cause of irreversible blindness worldwide. Primary open-angle
glaucoma (POAG), as the most prevalent form of glaucoma, is a complex inherited disorder …

Human cytochrome P450 enzymes (CYPs) play a critical role in various biological
processes and human diseases. CYP1 family members, including CYP1A1, CYP1A2, and …

Glaucoma is a leading cause of blindness, estimated to affect 60 million people by 2010,
and represents a heterogeneous group of neurodegenerative disease. The two major types …

Glaucoma, a leading cause of blindness worldwide, is characterized by progressive optic
nerve damage, usually associated with intraocular pressure. Although the clinical …

Glaucoma is a family of diseases whose pathology is defined by the progressive loss of
retinal ganglion cells. Clinically, glaucoma presents as a distinctive optic neuropathy with …

Primary open angle glaucoma (POAG), a major cause of blindness worldwide, is a complex
disease with a significant genetic contribution. We performed Exome Array (Illumina) …

Glaucoma is a heterogeneous group of optic neuropathies that manifests by optic nerve
head cupping or degeneration of the optic nerve, resulting in a specific pattern of visual field …