None of the proposed mechanisms of Alzheimer's disease (AD) fully explains the distribution
patterns of the neuropathological changes at the cellular and regional levels, and their …

Alzheimer's disease is of major concern all over the world due to a number of factors
including (i) an aging population (ii) increasing life span and (iii) lack of effective …

The brain noradrenergic system supplies the neurotransmitter norepinephrine throughout
the brain via widespread efferent projections, and plays a pivotal role in modulating …

Alzheimer's disease (AD) is a chronic neurodegenerative disorder, in which multiple risk
factors converge. Despite the complexity of the etiology of the disease, synaptic failure is the …

Peering into the field of Alzheimer's disease (AD), the outsider realizes that many of the
therapeutic strategies tested (in animal models) have been successful. One also may notice …

The Alzheimer's disease (AD) epidemic is a looming crisis, with an urgent need for new
therapies to delay or prevent symptom onset and progression. There is growing awareness …

Involvement of life stress in Late-Onset Alzheimer's Disease (LOAD) has been evinced in
longitudinal cohort epidemiological studies, and endocrinologic evidence suggests …

The complexity of Alzheimer's disease (AD) calls for search of multifunctional compounds as
potential candidates for effective therapy. A series of phthalimide and saccharin derivatives …

Diet supplementation with ketone bodies (acetoacetate and β‐hydroxybuturate) or medium‐
length fatty acids generating ketone bodies has consistently been found to cause modest …

Alzheimer's disease (AD) is a complex age-related neurodegenerative disease, associated
with central and peripheral metabolic anomalies, such as impaired glucose utilization and …