The use of decellularized skeletal muscle (DSM) as a cell substrate and scaffold for the
repair of volumetric muscle loss injuries has shown therapeutic promise. The performance of …

The mechanical properties of hydrogels used in biomaterials and tissue engineering
applications are critical determinants of their functionality. Despite the recent rise of additive …

Real-time simulation of organs increases comfort and safety for patients during the surgery.
Proper generalized decomposition (PGD) is an efficient numerical method with coordinate …

Currently little is known about the biomechanical environment in decellularized tissue. The
goal of this research is to quantify the mechanical microenvironment in decellularized liver …

Successful stem cell applications could have a significant impact on the medical field, where
many lives are at stake. However, the translation of stem cells to the clinic could be improved …

Biomaterials for tissue regeneration must mimic the biophysical properties of the native
physiological environment. A protein engineering approach allows the generation of protein …

Basement membranes (BMs) are thin layers of condensed extracellular matrix proteins
serving as permeability filters, cellular anchoring sites, and barriers against cancer cell …

Decellularization has been applied to many tissues and organs to obtain biomaterials for
applications in tissue engineering. In this study, decellularization and characterization of …

The decellularization method efficacy varies depending on the tissue type. There are
commonly used physical, chemical and enzymatic methods. Most of the methods affect the …

Maintaining hepatic functional characteristics in-vitro is considered one of the main
challenges in engineering liver tissue. As hepatocytes cultured ex-vivo are deprived of their …