Protective effects of quercetin on traumatic brain injury induced inflammation and oxidative stress in cortex through activating Nrf2/HO-1 pathway.

J Song, G Du, H Wu, X Gao, Z Yang, B Liu… - Restorative Neurology …, 2021 - europepmc.org
Background Traumatic brain injury (TBI) has been a serious public health issue. Clinically,
there is an urgent need for agents to ameliorate the neuroinflammation and oxidative stress …

Survival Following Traumatic Brain Injury in Drosophila Is Increased by Heterozygosity for a Mutation of the NF-κB Innate Immune Response Transcription Factor …

LC Swanson, EA Trujillo, GH Thiede… - Genetics, 2020 - academic.oup.com
Survival Following Traumatic Brain Injury in Drosophila Is Increased by Heterozygosity for a
Mutation of the NF-κB Innate Immune Response Transcription Factor Relish | Genetics | Oxford …

[HTML][HTML] Inflammation biomarkers IL‑6 and IL‑10 may improve the diagnostic and prognostic accuracy of currently authorized traumatic brain injury tools

C Tsitsipanis, M Miliaraki, E Paflioti… - Experimental and …, 2023 - spandidos-publications.com
Traumatic brain injury (TBI) is currently one of the leading causes of mortality and disability
worldwide. At present, no reliable inflammatory or specific molecular neurobiomarker exists …

[HTML][HTML] Rethinking neuroprotection in severe traumatic brain injury: toward bedside neuroprotection

T Zoerle, M Carbonara, ER Zanier, F Ortolano… - Frontiers in …, 2017 - frontiersin.org
Neuroprotection after traumatic brain injury (TBI) is an important goal pursued strenuously in
the last 30 years. The acute cerebral injury triggers a cascade of biochemical events that …

Altered hippocampal neurogenesis during the first 7 days after a fluid percussion traumatic brain injury

LA Shapiro - Cell transplantation, 2017 - journals.sagepub.com
Traumatic brain injury (TBI) is a devastating disorder causing negative outcomes in millions
of people each year. Despite the alarming number of brain injuries and the long-term …

Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis

R Immonen, G Smith, RD Brady, D Wright, L Johnston… - Epilepsy research, 2019 - Elsevier
Preclinical imaging studies of posttraumatic epileptogenesis (PTE) have largely been proof-
of-concept studies with limited animal numbers, and thus lack the statistical power for …

Incretin mimetics as rational candidates for the treatment of traumatic brain injury

EJ Glotfelty, TE Delgado… - ACS pharmacology & …, 2019 - ACS Publications
Traumatic brain injury (TBI) is becoming an increasing public health issue. With an annually
estimated 1.7 million TBIs in the United States (US) and nearly 70 million worldwide, the …

Blueberry supplementation mitigates altered brain plasticity and behavior after traumatic brain injury in rats

G Krishna, Z Ying… - Molecular nutrition & food …, 2019 - Wiley Online Library
Scope Traumatic brain injury (TBI) compromises neuronal function required for hippocampal
synaptic plasticity and cognitive function. Despite the high consumption of blueberries …

[HTML][HTML] EphB3 signaling induces cortical endothelial cell death and disrupts the blood–brain barrier after traumatic brain injury

P Assis-Nascimento, Y Tsenkina, DJ Liebl - Cell death & disease, 2018 - nature.com
Damage to the cerebrovascular network is a major contributor to dysfunction in patients
suffering from traumatic brain injury (TBI). Vessels are composed of lumen-forming …

[HTML][HTML] Iron metabolism disorders for cognitive dysfunction after mild traumatic brain injury

S Huang, S Li, H Feng, Y Chen - Frontiers in neuroscience, 2021 - frontiersin.org
Traumatic brain injury (TBI) is one of the most harmful forms of acute brain injury and
predicted to be one of the three major neurological diseases that cause neurological …