Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Simple Summary P-element-induced wimpy testis-interacting RNAs (piRNAs) are a novel
class of small regulatory RNAs that often bind to PIWI proteins. First identified in animal germ …

Background Serum exosome-based liquid biopsy has significant advantages for screening
and diagnosing hepatocellular carcinoma (HCC). P-element-induced wimpy testis (PIWI) …

Emerging studies demonstrate that PIWI-interacting RNAs (piRNAs) are associated with
various human cancers. This study aimed to evaluate the urinary extracellular vesicles (EVs) …

Non-small cell lung cancer (NSCLC) is a major cause of death in those with malignant
tumors. To achieve the early diagnosis of NSCLC, we investigated serum-derived Piwi …

Simple Summary Pancreatic cancer is the seventh leading cause of cancer related death
worldwide. In the United States, pancreatic cancer remains the fourth leading cause of …

Lung cancer has a high morbidity and mortality rate, and affected patients have a poor
prognosis and low survival. The therapeutic approaches for lung cancer treatment, including …

Liquid biopsy is a valuable tool in oncology with its advantages of non-invasiveness,
longitudinal sampling, and capturing the intra-and inter-tumor heterogeneity. Small …

The state of host cells is reflected in the cargo carried by their extracellular vesicles (EVs).
This makes EV a potential source of biomarkers for human diseases. Piwi-interacting RNA …

MicroRNAs (miRNAs) can regulate the expression of genes involved in the establishment of
the window of implantation (WOI) in the endometrium. Recent studies indicated that cell-free …