[HTML][HTML] Bone-targeting exosome nanoparticles activate Keap1/Nrf2/GPX4 signaling pathway to induce ferroptosis in osteosarcoma cells

W Chen, Z Li, N Yu, L Zhang, H Li, Y Chen… - Journal of …, 2023 - Springer
Background In recent years, the development of BMSCs-derived exosomes (EXO) for the
treatment of osteosarcoma (OS) is a safe and promising modality for OS treatment, which …

[HTML][HTML] CAR‑T cell therapy: A breakthrough in traditional cancer treatment strategies

D Sun, X Shi, S Li, X Wang… - Molecular …, 2024 - … .spandidos-publications.com
Chimeric antigen receptor (CAR)‑T cell therapy is an innovative approach to immune cell
therapy that works by modifying the T cells of a patient to express the CAR protein on their …

Advancements in osteosarcoma management: integrating immune microenvironment insights with immunotherapeutic strategies

H Liang, M Cui, J Tu, X Chen - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
Osteosarcoma, a malignant bone tumor predominantly affecting children and adolescents,
presents significant therapeutic challenges, particularly in metastatic or recurrent cases …

[HTML][HTML] Microalgae-based drug delivery system for tumor microenvironment photo-modulating and synergistic chemo-photodynamic therapy of osteosarcoma

F Liang, X An, R Wang, W Wu, L Yang, Y Zheng… - Engineered …, 2024 - Elsevier
Osteosarcoma (OS) is one of the most common malignant tumors in children and young
adults. As chemotherapy and other therapies are limited by low therapeutic efficiency …

Advanced strategies in improving the immunotherapeutic effect of CAR‐T cell therapy

M Wang, L Jia, X Dai, X Zhang - Molecular Oncology, 2024 - Wiley Online Library
Chimeric antigen receptor (CAR‐T) cell therapy is a newly developed immunotherapy
strategy and has achieved satisfactory outcomes in the treatment of hematological …

RNA Isoforms as Broad Targets for Cancer Immunotherapy

G Li, N Salomonis - DNA and Cell Biology, 2024 - liebertpub.com
While immunotherapy is typically reserved for cancer patients with a high mutational burden,
neoantigens produced from post-transcriptional regulation provide a possible untapped …

Construction of a prognostic model with CAFs for predicting the prognosis and immunotherapeutic response of lung squamous cell carcinoma

X Zhang, Q Xiao, C Zhang, Q Zhou… - Journal of Cellular and …, 2024 - Wiley Online Library
Lung squamous cell carcinoma (LUSC) is one of the subtypes of lung cancer (LC) that
contributes to approximately 25%–30% of its prevalence. Cancer‐associated fibroblasts …

Kinetics of cancer metastasis

VP Zhdanov - Biosystems, 2024 - Elsevier
The formation of metastases during cancer is now considered to be induced by migrating
metastatic stem cells (MetSCs) in preexisting niches or niches induced by MetSCs or tumor …

[PDF][PDF] Humanization of Chimeric Antigen Receptors (CARs) OSCAR-1 and OSCAR-3

P Ahnstrøm - 2023 - duo.uio.no
Osteosarcoma (OS), a malignant tumor of the bone, is one of the most common forms of
cancer among adolescence, presenting in more than 5 per 1 million children under 15 years …

Targeted Biological and Cellular Immunotherapies for Osteosarcoma

GM Robbins - 2023 - search.proquest.com
Osteosarcoma (OSA) is the most common cancer of the bone and third most common cancer
diagnosed in children and adolescent. The five-year survival rate for OSA patients …