Low grade gliomas are the most frequent brain tumors in children and encompass a
spectrum of histologic entities which are currently assigned World Health Organisation …

Background Nowadays, conventional medical treatments such as surgery, radiotherapy, and
chemotherapy cannot cure all types of cancer. A promising approach to treat solid tumors is …

Cellular senescence is an important factor in aging and many age-related diseases, but
understanding its role in health is challenging due to the lack of exclusive or universal …

Cancer along with cardiovascular disease are the main causes of death in the industrialised
countries around the World. Conventional cancer treatments are losing their therapeutic …

Recent studies suggest that cuproptosis, a novel mode of cell death, may be associated with
the development of cancer. However, no studies are showing its role in tumorigenesis …

Purpose: Ribociclib (an oral, highly specific cyclin-dependent kinase 4/6 inhibitor) inhibits
tumor growth in preclinical models with intact retinoblastoma protein (Rb+). This first-in …

Hepatocellular carcinoma (HCC) is a common malignancy and one of the leading causes of
cancer-related death. The biological process of HCC is complex, with multiple factors …

Aging is a biological feature that is characterized by gradual degeneration of function in
cells, tissues, organs, or an intact organism due to the accumulation of environmental factors …

Background Malignant pleural and peritoneal mesotheliomas are rare malignancies with
unacceptable poor prognoses and limited treatment options. The genomic landscape is …

Background: High-risk human papillomaviruses (HPVs) are etiologic agents for anogenital
tract cancers and have been detected in head and neck squamous cell carcinomas …