Formaldehyde toxicity reports from in vitro and in vivo studies: a review and updated data

L Bernardini, E Barbosa, MF Charão… - Drug and chemical …, 2022 - Taylor & Francis
Formaldehyde (FA) is a xenobiotic air pollutant and its universal distribution causes a
widespread exposure to humans. This review aimed to bring updated information …

[HTML][HTML] Relationship between formaldehyde exposure, respiratory irritant effects and cancers: a review of reviews

G La Torre, T Vitello, RA Cocchiara, C Della Rocca - Public Health, 2023 - Elsevier
Objectives Formaldehyde is an organic compound used in the production of resins, paper,
wood plywood, solvents and cleaning products. Formaldehyde is also present when tobacco …

Nanomaterials for sensing of formaldehyde in air: Principles, applications, and performance evaluation

D Kukkar, K Vellingiri, R Kaur, SK Bhardwaj, A Deep… - Nano Research, 2019 - Springer
Despite the improvement in sensing technologies, detection of small and highly reactive
molecules like formaldehyde remains a highly challenging area of research. Applications of …

A review of stable isotope labeling and mass spectrometry methods to distinguish exogenous from endogenous DNA adducts and improve dose–response …

K Lu, YC Hsiao, CW Liu, R Schoeny… - Chemical Research …, 2021 - ACS Publications
Cancer remains the second most frequent cause of death in human populations worldwide,
which has been reflected in the emphasis placed on management of risk from environmental …

Does occupational exposure to formaldehyde cause hematotoxicity and leukemia-specific chromosome changes in cultured myeloid progenitor cells?

KA Mundt, AE Gallagher, LD Dell… - Critical Reviews in …, 2017 - Taylor & Francis
Several cross-sectional studies of a single population of workers exposed to formaldehyde
at one of two factories using or producing formaldehyde–melamine resins in China have …

[HTML][HTML] Six years after the NRC review of EPA's Draft IRIS Toxicological Review of Formaldehyde: Regulatory implications of new science in evaluating formaldehyde …

KA Mundt, PR Gentry, LD Dell, JV Rodricks… - Regulatory Toxicology …, 2018 - Elsevier
Abstract Shortly after the International Agency for Research on Cancer (IARC) determined
that formaldehyde causes leukemia, the United States Environmental Protection Agency …

[HTML][HTML] Considerations for refining the risk assessment process for formaldehyde: Results from an interdisciplinary workshop

ME Andersen, PR Gentry, JA Swenberg… - Regulatory Toxicology …, 2019 - Elsevier
Anticipating the need to evaluate and integrate scientific evidence to inform new risk
assessments or to update existing risk assessments, the Formaldehyde Panel of the …

A critical appraisal of the sensitivity of in vivo genotoxicity assays in detecting human carcinogens

A Zeller, S Pfuhler, S Albertini, F Bringezu, A Czich… - …, 2018 - academic.oup.com
Genotoxicity testing is an important part of standard safety testing strategies. Animal studies
have always been a key component, either as a mandatory part of the regulatory test battery …

Dual effects of endogenous formaldehyde on the organism and drugs for its removal

J Chen, W Chen, J Zhang, H Zhao… - Journal of Applied …, 2024 - Wiley Online Library
Endogenous formaldehyde (FA) is produced in the human body via various mechanisms to
preserve healthy energy metabolism and safeguard the organism. However, endogenous …

Assessment of associations between inhaled formaldehyde and lymphohematopoietic cancer through the integration of epidemiological and toxicological evidence …

MJ Vincent, S Fitch, L Bylsma, C Thompson… - Toxicological …, 2024 - academic.oup.com
Formaldehyde is recognized as carcinogenic for the portal of entry sites, though conclusions
are mixed regarding lymphohematopoietic (LHP) cancers. This systematic review assesses …