[HTML][HTML] NSCLC biomarkers to predict response to immunotherapy with checkpoint inhibitors (ICI): from the cells to in vivo images

V Liberini, A Mariniello, L Righi, M Capozza… - Cancers, 2021 - mdpi.com
Simple Summary Lung cancer and in particular non-small cell lung cancer (NSCLC)
remains the leading cause of cancer-related death. The development of new therapeutic …

Efficacy evaluation of neoadjuvant immunotherapy plus chemotherapy for non-small-cell lung cancer: comparison of PET/CT with postoperative pathology

Y Cheng, Z Chen, J Huang, D Shao - European Radiology, 2023 - Springer
Objectives To assess the value of positron emission tomography/computed tomography
(PET/CT) in the efficacy evaluation of patients undergoing neoadjuvant immunotherapy plus …

[HTML][HTML] First-line pembrolizumab mono-or combination therapy of non-small cell lung cancer: baseline metabolic biomarkers predict outcomes

D Lang, L Ritzberger, V Rambousek, A Horner, R Wass… - Cancers, 2021 - mdpi.com
Simple Summary Positron-emission tomography/computed tomography (PET/CT) is used for
staging of non-small cell lung cancer (NSCLC) and can help to estimate prognosis in …

Utility of 18F-FDG PET/CT uptake values in predicting response to neoadjuvant chemoimmunotherapy in resectable non-small cell lung cancer

F Zhuang, E Haoran, J Huang, J Wu, L Xu, L Zhang… - Lung Cancer, 2023 - Elsevier
Introduction Reliable predictive markers are lacking for resectable non-small cell lung
cancer (NSCLC) patients treated with neoadjuvant chemoimmunotherapy. The present …

PET/CT for Target Delineation of Lung Cancer Before Radiation Therapy

F Manapov, C Eze, A Holzgreve, L Käsmann… - Seminars in Nuclear …, 2022 - Elsevier
In clinical routine of patients suffering from lung cancer, radiotherapy/radiation oncology
represents one of the therapeutic hallmarks in the multimodal treatment besides or in …

[HTML][HTML] MR-guided radiotherapy in node-positive non-small cell lung cancer and severely limited pulmonary reserve: a report proposing a new clinical pathway for the …

C Eze, E Lombardo, L Nierer, Y Xiong, M Niyazi… - Radiation …, 2022 - Springer
Introduction Online MR-guided radiotherapy (MRgRT) is a relatively novel advancement in
the field of radiation oncology, ensuring superior soft-tissue visualisation, allowing for online …

[HTML][HTML] Combined use of CYFRA 21-1 and CA 125 predicts survival of patients with metastatic NSCLC and stable disease in IMpower150

A Mang, W Zou, V Rolny, M Reck, D Cigoianu… - Tumor …, 2024 - content.iospress.com
BACKGROUND: Patients with non-small cell lung cancer (NSCLC) and stable disease (SD)
have an unmet clinical need to help guide early treatment adjustments. OBJECTIVE: To …

Controllable Dopamine Conjugation Boosts Fluorescence, Biocompatibility, and PET Imaging‐Guided Toxicity Assessment of Polycations

M Zhao, X Guo, C Su, M Li, X Wang… - Advanced Functional …, 2024 - Wiley Online Library
As well known in bioactives delivery and cancer/inflammation theranostics, polycations have
recently extended their biomedical potentials in reducing visceral fat, embolizing body fluid …

A novel analytical approach for outcome prediction in newly diagnosed NSCLC based on [18F]FDG PET/CT metabolic parameters, inflammatory markers, and clinical …

L Zhang, C Xu, X Zhang, J Wang, H Jiang, J Chen… - European …, 2023 - Springer
Objectives To develop a novel analytical approach based on 18F-fluorodeoxyglucose ([18F]
FDG) positron emission tomography (PET) metabolic parameters, serum inflammatory …

Forging a path for metformin use in inoperable locally advanced non–small cell lung cancer

C Eze, C Belka, F Manapov - JAMA oncology, 2021 - jamanetwork.com
Metformin, an antidiabetic drug, has demonstrated a broad spectrum of antitumor activity in
preclinical studies: mechanistic effects include inhibition of complex I of the mitochondria …