Iron is a critical element for living cells in terrestrial life. Although iron metabolism is strictly
controlled in the body, disturbance of iron homeostasis under certain type of condition leads …

It is well accepted that CNS inflammation has a role in the progression of chronic
neurodegenerative disease, although the mechanisms through which this occurs are still …

NOD-like receptor (NLR), family pyrin domain containing 3 (NLRP3) assembles a protein
complex known as the NLRP3 inflammasome upon sensing certain pathogen products or …

To open the e-book, you will require Adobe Reader software program. If you do not have
Adobe Reader already installed on your computer, you can download the installer and …

Although the innate immune response to induce postischemic inflammation is considered as
an essential step in the progression of cerebral ischemia injury, the role of innate immunity …

In the complex interplay between malignant cells and their microenvironment, caspase-1
activation complexes (inflammasomes) have contrasting roles. Inflammasomes may operate …

The crosstalk between inflammation and tumorigenesis is now clearly established. However,
how inflammation is elicited in the metastatic environment and the corresponding …

Chronic inflammatory responses have long been observed to be associated with various
types of cancer and play decisive roles at different stages of cancer development …

Stimulator of interferon genes (STING, also named MITA, MYPS, or ERIS) is an intracellular
DNA sensor that induces type I interferon through its interaction with TANK-binding kinase 1 …

The modulation of macroautophagy is now recognized as one of the hallmarks of cancer
cells. There is accumulating evidence that autophagy plays a role in the various stages of …