Micronutrient deficiencies in pregnancy worldwide: health effects and prevention
AD Gernand, KJ Schulze, CP Stewart… - Nature Reviews …, 2016 - nature.com
Micronutrients, vitamins and minerals accessible from the diet, are essential for biologic
activity. Micronutrient status varies widely throughout pregnancy and across populations …
activity. Micronutrient status varies widely throughout pregnancy and across populations …
The continuing challenge of understanding, preventing, and treating neural tube defects
JB Wallingford, LA Niswander, GM Shaw, RH Finnell - Science, 2013 - science.org
Background Neural tube defects (NTDs) are debilitating birth defects involving the central
nervous system (CNS). Despite recent advances, NTDs represent the second most common …
nervous system (CNS). Despite recent advances, NTDs represent the second most common …
[图书][B] Nutritional epidemiology
W Willett - 2012 - books.google.com
This text is intended for those who wish to understand the complex relationships between
diet and risks of important diseases, such as cancer and cardiovascular disease. It is aimed …
diet and risks of important diseases, such as cancer and cardiovascular disease. It is aimed …
Neural tube defects, folic acid and methylation
A Imbard, JF Benoist, HJ Blom - International journal of environmental …, 2013 - mdpi.com
Neural tube defects (NTDs) are common complex congenital malformations resulting from
failure of the neural tube closure during embryogenesis. It is established that folic acid …
failure of the neural tube closure during embryogenesis. It is established that folic acid …
Frizzled receptors in development and disease
Frizzled proteins are the principal receptors for the Wnt family of ligands. They mediate
canonical Wnt signaling together with Lrp5 and Lrp6 coreceptors. In conjunction with Celsr …
canonical Wnt signaling together with Lrp5 and Lrp6 coreceptors. In conjunction with Celsr …
Folic acid supplementation in pregnancy and implications in health and disease
S Barua, S Kuizon, MA Junaid - Journal of biomedical science, 2014 - Springer
Maternal exposure to dietary factors during pregnancy can influence embryonic
development and may modulate the phenotype of offspring through epigenetic …
development and may modulate the phenotype of offspring through epigenetic …
Yap controls notochord formation and neural tube patterning by integrating mechanotransduction with FoxA2 and Shh expression
Correct notochord and neural tube (NT) formation is crucial to the development of the central
nervous system and midline structures. Integrated biochemical and biophysical signaling …
nervous system and midline structures. Integrated biochemical and biophysical signaling …
Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes
Frizzled (Fz) 2 and Fz7, together with Fz1, form a distinct subfamily within the Frizzled family
of Wnt receptors. Using targeted gene deletion, we show that: Fz7−/− mice exhibit tail …
of Wnt receptors. Using targeted gene deletion, we show that: Fz7−/− mice exhibit tail …
Spina bifida management
LA Phillips, JM Burton, SH Evans - … in pediatric and adolescent health care, 2017 - Elsevier
Myelomeningocele, commonly known as spina bifida, is a birth defect in which the spinal
cord does not develop properly due to incomplete closure of the neural tube at 28 days of …
cord does not develop properly due to incomplete closure of the neural tube at 28 days of …
Causes and consequences of impaired methionine synthase activity in acquired and inherited disorders of vitamin B12 metabolism
JL Guéant, RM Guéant-Rodriguez… - Critical reviews in …, 2022 - Taylor & Francis
Abstract Methyl-Cobalamin (Cbl) derives from dietary vitamin B12 and acts as a cofactor of
methionine synthase (MS) in mammals. MS encoded by MTR catalyzes the remethylation of …
methionine synthase (MS) in mammals. MS encoded by MTR catalyzes the remethylation of …