Ankylosing spondylitis and axial spondyloarthritis

JD Taurog, A Chhabra, RA Colbert - New England Journal of …, 2016 - Mass Medical Soc
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The early phases of ankylosing spondylitis: emerging insights from clinical and basic science

A Watad, C Bridgewood, T Russell… - Frontiers in …, 2018 - frontiersin.org
In our paper, we discuss how the early phases of ankylosing spondylitis (AS) are linked to
peri-firbocartilagenous osteitis in the sacroiliac joint and entheseal bone related anchoring …

Immunomodulatory role of neuropeptides in the cornea

S Puri, BM Kenyon, P Hamrah - Biomedicines, 2022 - mdpi.com
The transparency of the cornea along with its dense sensory innervation and resident
leukocyte populations make it an ideal tissue to study interactions between the nervous and …

Causes and consequences of endoplasmic reticulum stress in rheumatic disease

F Navid, RA Colbert - Nature Reviews Rheumatology, 2017 - nature.com
Rheumatic diseases represent a heterogeneous group of inflammatory conditions, many of
which involve chronic activation of both innate and adaptive immune responses by multiple …

The role of gut microbiota and IL-23/IL-17 pathway in ankylosing spondylitis immunopathogenesis: New insights and updates

F Babaie, M Hasankhani, H Mohammadi… - Immunology letters, 2018 - Elsevier
Ankylosing spondylitis (AS) is a type of arthritis that is referred to a group of chronic immune-
mediated inflammatory diseases termed as seronegative spondyloarthropathies or …

Uncovering the underworld of axial spondyloarthritis

S Del Vescovo, V Venerito, C Iannone… - International journal of …, 2023 - mdpi.com
Axial spondyloarthritis (axial-SpA) is a multifactorial disease characterized by inflammation
in sacroiliac joints and spine, bone reabsorption, and aberrant bone deposition, which may …

HLA-B* 27 and ankylosing spondylitis: 50 years of insights and discoveries

MA Khan - Current Rheumatology Reports, 2023 - Springer
Abstract Purpose of Review To commemorate the 50th anniversary of the groundbreaking
discovery of a remarkably strong association between HLA-B* 27 and ankylosing spondylitis …

The interplay between HLA-B27 and ERAP1/ERAP2 aminopeptidases: from anti-viral protection to spondyloarthritis

C Vitulano, V Tedeschi, F Paladini… - Clinical & …, 2017 - academic.oup.com
The human leukocyte antigen class I gene HLA-B27 is the strongest risk factor for
ankylosing spondylitis (AS), a chronic inflammatory arthritic disorder. More recently, the …

[HTML][HTML] Antigen-specific immune reactions by expanded CD8+ T cell clones from HLA-B* 27-positive patients with spondyloarthritis

K Deschler, J Rademacher, SM Lacher, A Huth… - Journal of …, 2022 - Elsevier
Spondyloarthritis (SpA) is a chronic inflammatory disease that is tightly linked to HLA-B* 27
but the pathophysiological basis of this link is still unknown. It is discussed whether either …

The role of HLA-B* 27 in spondyloarthritis

RA Colbert, F Navid, T Gill - Best practice & research Clinical rheumatology, 2017 - Elsevier
The mechanism by which HLA-B* 27 predisposes to spondyloarthritis remains unresolved.
Arthritogenic peptides have not been defined in humans and are not involved in …