Despite improvements in contemporary medical and surgical therapies, cardiovascular
disease (CVD) remains a significant cause of worldwide morbidity and mortality; more …

Resent study suggests that c-kit+ cells in bone marrow-derived MSCs may differentiate
toward cardiamyocytes. However, the properties of c-kit+ MSCs remain unclear. This study …

In the field of cell therapy for heart disease, a new paradigm of repeated dosing of cells has
recently emerged. However, the lack of a repeatable cell delivery method in preclinical …

Cardiac fibrosis is a significant contributor to heart failure, a condition that continues to affect
a growing number of patients worldwide. Various cardiovascular comorbidities can …

Purpose Myocardial healing following myocardial infarction (MI) is a complex process that is
yet to be fully understood. Clinical attempts in regeneration of the injured myocardium using …

After an ischemic event, there is activation of fibroblasts leading to scar formation. It is critical
to limit the profibrotic remodeling and activate the reparative remodeling phase to limit …

Aims Because the mechanism of mature cardiomyocyte (CM) development from cardiac
stem cells (CSCs) is not fully understood, we explored the involvement of CSCs into two …

心脏淋巴系统在心肌损伤后修复过程中发挥重要作用， 其可能通过维持体液稳态和控制炎症
反应来调控正常组织稳态和自然再生。 心脏淋巴系统在心肌损伤后激活并参与心脏疤痕形成 …

Cell therapy is a promising strategy in which living cells or cellular materials are delivered to
treat a variety of diseases. Here, we developed an electrospray bioprinting method to rapidly …

For nearly a century, the adult heart was considered as a post-mitotic organ. The discovery
of a resident cardiac stem cell (CSC) population in the heart has dramatically undermined …