[HTML][HTML] Next-generation influenza vaccines: opportunities and challenges

CJ Wei, MC Crank, J Shiver, BS Graham… - Nature reviews Drug …, 2020 - nature.com
Seasonal influenza vaccines lack efficacy against drifted or pandemic influenza strains.
Developing improved vaccines that elicit broader immunity remains a public health priority …

[HTML][HTML] An overview of influenza viruses and vaccines

RF Nuwarda, AA Alharbi, V Kayser - Vaccines, 2021 - mdpi.com
Influenza remains one of the major public health concerns because it causes annual
epidemics and can potentially instigate a global pandemic. Numerous countermeasures …

[HTML][HTML] A year of terror and a century of reflection: perspectives on the great influenza pandemic of 1918–1919

ME Nickol, J Kindrachuk - BMC infectious diseases, 2019 - Springer
Background In the spring of 1918, the “War to End All Wars”, which would ultimately claim
more than 37 million lives, had entered into its final year and would change the global …

[HTML][HTML] Current and future influenza vaccines

S Yamayoshi, Y Kawaoka - Nature medicine, 2019 - nature.com
Although antiviral drugs and vaccines have reduced the economic and healthcare burdens
of influenza, influenza epidemics continue to take a toll. Over the past decade, research on …

[HTML][HTML] The 2020 race towards SARS-CoV-2 specific vaccines

TM Karpiński, M Ożarowski… - Theranostics, 2021 - ncbi.nlm.nih.gov
The global outbreak of a novel severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) highlighted a requirement for two pronged clinical interventions such as …

Swine influenza virus: Current status and challenge

W Ma - Virus research, 2020 - Elsevier
Since swine influenza virus was first isolated in 1930, it has become endemic in pigs
worldwide. Although large amount of swine influenza vaccines has been used in swine …

[HTML][HTML] Vaccines against major poultry viral diseases: strategies to improve the breadth and protective efficacy

R Ravikumar, J Chan, M Prabakaran - Viruses, 2022 - mdpi.com
The poultry industry is the largest source of meat and eggs for human consumption
worldwide. However, viral outbreaks in farmed stock are a common occurrence and a major …

[HTML][HTML] Development of effective anti-influenza drugs: congeners and conjugates–a review

JJ Shie, JM Fang - Journal of Biomedical Science, 2019 - Springer
Influenza is a long-standing health problem. For treatment of seasonal flu and possible
pandemic infections, there is a need to develop new anti-influenza drugs that have good …

Intranasal vaccination with influenza HA/GO-PEI nanoparticles provides immune protection against homo-and heterologous strains

C Dong, Y Wang, GX Gonzalez, Y Ma… - Proceedings of the …, 2021 - National Acad Sciences
Intranasal (in) immunization is a promising vaccination route for infectious respiratory
diseases such as influenza. Recombinant protein vaccines can overcome the safety …

[HTML][HTML] Novel platforms for the development of a universal influenza vaccine

A Kumar, TS Meldgaard, S Bertholet - Frontiers in immunology, 2018 - frontiersin.org
Despite advancements in immunotherapeutic approaches, influenza continues to cause
severe illness, particularly among immunocompromised individuals, young children, and …