Oxidative stress (OS) is defined as a disturbance in the prooxidant‐antioxidant balance of
the cell, in favor of the former, which results in the antioxidant capacity of the cell to be …

The sirtuin family of nicotinamide adenine dinucleotide–dependent deacylases (SIRT1–7)
are thought to be responsible, in large part, for the cardiometabolic benefits of lean diets and …

Diabetic retinopathy (DR) and other diabetic vascular complications are the leading cause of
death and disability in patients with suboptimum glycemic control. In the pathogenesis of …

Cardiovascular complications are considered one of the leading causes of morbidity and
mortality among diabetic patients. Diabetic cardiomyopathy (DCM) is a type of …

Abstract Type 2 diabetes mellitus (DM2) follows impaired glucose tolerance in obesity and is
frequently associated with hypertension, causing adverse myocardial remodelling and …

Asians are more susceptible to type 2 diabetes mellitus (T2D) and its coronary heart disease
(CHD) complications than the Western populations, possibly due to genetic factors, higher …

Background: Since its discovery, poly (ADP-ribose) polymerase 1 (PARP-1) has been
extensively studied due to its regulatory role in numerous biologically crucial pathways …

Abstract Objective Paeonia lactiflora Pall has long been recognized as an anti-inflammatory
traditional Chinese herbal medicine. We aimed to study the pharmacological action of …

Hyperbaric oxygen therapy (HBOT) is frequently used after soft tissue injuries and in diabetic
patients with ulcerated wounds; however, its ability to increase oxidative stress casts doubts …

Importance Tumor necrosis factor α (TNF-α) is a proinflammatory cytokine with manifold
consequences for mammalian pathophysiology, including cardiovascular disease. A deeper …