Background Misconceptions about ADHD stigmatize affected people, reduce credibility of
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings …

The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Behaviors and disorders related to self-regulation, such as substance use, antisocial
behavior and attention-deficit/hyperactivity disorder, are collectively referred to as …

There is increasing academic and clinical interest in how “lifestyle factors” traditionally
associated with physical health may also relate to mental health and psychological well …

Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder
with a major genetic component. Here, we present a genome-wide association study meta …

Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …

Microglia and complement can mediate neurodegeneration in Alzheimer's disease (AD). By
integrative multi-omics analysis, here we show that astrocytic and microglial proteins are …

Genome-wide association studies of neurological diseases have identified thousands of
variants associated with disease phenotypes. However, most of these variants do not alter …

Delineating the gene-regulatory programs underlying complex cell types is fundamental for
understanding brain function in health and disease. Here, we comprehensively examined …